Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980856 | 0.82 | MAPK1 (0.40) | KMT2AMAPK1TDP1HSD11B1MEN1 | |
| SCHEMBL9843107 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMAPK1TDP1ALDH1A1 | |
| SCHEMBL3864254 | 0.80 | TBXA2R (0.45) | KMT2AMAPK1TDP1ALDH1A1HSD11B1 | |
| SCHEMBL11511800 | 0.79 | KMT2A (0.45) | KMT2AMAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL18837940 | 0.76 | TDP1 (0.58) | SMN1; SMN2KMT2ATDP1LMNAMEN1 | |
| SCHEMBL11482764 | 0.75 | KMT2A (0.53) | SMN1; SMN2KMT2AMAPK1ALDH1A1HSD11B1 | |
| SCHEMBL28244926 | 0.74 | LMNA (0.65) | SMN1; SMN2KMT2AMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL6999742 | 0.74 | BMP1 (0.65) | SMN1; SMN2KMT2AALDH1A1LMNATP53 | |
| SCHEMBL8657199 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AALDH1A1L3MBTL1ALOX5 | |
| SCHEMBL3899542 | 0.74 | KMT2A (0.47) | SMN1; SMN2KMT2AMAPK1ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186967-A1 | Acylresorcinol derivatives are selective vitronectin receptor inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186967-A1 | Acylresorcinol derivatives are selective vitronectin receptor inhibitors | ASGR1, TEK, APLNR | SMN1; SMN2 3867/4885KMT2A 3514/4885MAPK1 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.