Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089594 | 0.95 | — | — | |
| SCHEMBL7200643 | 0.90 | PKM (0.33) | CCR5LMNA | |
| SCHEMBL4873613 | 0.88 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL4875121 | 0.88 | CYP2D6 (0.36) | CCR5LMNASMN1; SMN2 | |
| SCHEMBL4870208 | 0.86 | ACHE (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL4870439 | 0.86 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL7158802 | 0.85 | LMNA (0.30) | LMNASMN1; SMN2 | |
| SCHEMBL4874224 | 0.85 | LMNA (0.30) | LMNASMN1; SMN2 | |
| SCHEMBL4874284 | 0.85 | CCR2 (0.33) | CCR5 | |
| SCHEMBL4873767 | 0.84 | NMT1 (0.33) | CCR5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |