Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200638 | 0.88 | TSHR (0.34) | — | |
| SCHEMBL4875121 | 0.88 | CYP2D6 (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL7158804 | 0.85 | CCR5 (0.30) | LMNASMN1; SMN2 | |
| SCHEMBL4873613 | 0.85 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL4870439 | 0.83 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL4870208 | 0.83 | ACHE (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL7200643 | 0.83 | PKM (0.33) | LMNA | |
| SCHEMBL4870323 | 0.83 | CYP2D6 (0.35) | LMNA | |
| SCHEMBL4874284 | 0.82 | CCR2 (0.33) | — | |
| SCHEMBL4874224 | 0.82 | LMNA (0.30) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |