SCHEMBL715969

SCHEMBL715969

O=C(O)C(C(F)(F)F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
TET2 Q6N021 1/20 0.33
ACLY P53396 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068542 0.96 THRB (0.41) THRBALDH1A1L3MBTL1TSHRTP53
SCHEMBL5915198 0.83 THRB (0.50) THRBALDH1A1L3MBTL1TSHRTP53
SCHEMBL15362567 0.78 TSHR (0.38) THRBALDH1A1L3MBTL1TSHR
SCHEMBL3959926 0.78 THRB (0.40) THRBALDH1A1L3MBTL1
SCHEMBL18799050 0.76 ALDH1A1 (0.36) THRBALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL27950682 0.75
SCHEMBL3138239 0.72 THRB (0.32) THRB
Trifluoroacetic Acid SCHEMBL28581168 0.72 ALDH1A1 (0.40) THRBALDH1A1L3MBTL1TSHRTP53
Trifluoroacetic Acid SCHEMBL4598430 0.70
Trifluoroacetic Acid SCHEMBL2484766 0.70 ALDH1A1 (0.44) THRBALDH1A1L3MBTL1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10040732-B2 Process for the production of biaryl compounds DSM IP ASSETS B.V. (NL) 2018-08-07 US claimed
EP-3169651-B1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS BV (NL) 2018-06-20 EP claimed
US-20170210681-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS B.V. (NL) 2017-07-27 US claimed
EP-3169651-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP Assets B.V. (NL) 2017-05-24 EP claimed
WO-2016008931-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS B.V. (NL) 2016-01-21 WO claimed
JP-62204823-A None JP disclosed
JP-62097124-A None JP disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-10040732-B2 Process for the production of biaryl compounds DSM IP ASSETS B.V. (NL) 2018-08-07 US disclosed
EP-3169651-B1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS BV (NL) 2018-06-20 EP disclosed
US-20170210681-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS B.V. (NL) 2017-07-27 US disclosed
EP-3169651-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP Assets B.V. (NL) 2017-05-24 EP disclosed
WO-2016008931-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS B.V. (NL) 2016-01-21 WO disclosed
US-8357765-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-22 US disclosed
US-8288490-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-20120053311-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
JP-S62204823-A GAS SEPARATION ELEMENT WITH HIGH SELECTIVE PERMEABILITY NIPPON OIL & FATS CO LTD 1987-09-09 JP disclosed
JP-S6297124-A MAGNETIC RECORDING MEDIUM HITACHI LTD 1987-05-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210681-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DDT, COASY, ALDH3A1 THRB 3472/4885ALDH1A1 52/4885L3MBTL1 2938/4885
US-10040732-B2 Process for the production of biaryl compounds DDT, COASY, ALDH3A1 THRB 3472/4885ALDH1A1 52/4885L3MBTL1 2938/4885
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION PPOX, SOD1, AP1M1 THRB 4450/4885ALDH1A1 1442/4885L3MBTL1 4882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.