SCHEMBL7160494

SCHEMBL7160494

C=CCB(c1ccc(C)cc1)c1ccc(C)cc1CC=C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 4/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 3/20 0.32
GAA P10253 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALOX12 P18054 1/20 0.32
HTT P42858 1/20 0.32
TP53 P04637 1/20 0.30
GABRA1 P14867 2/20 0.30
GABRB2 P47870 2/20 0.30
ALDH2 P05091 1/20 0.30
AKR1B1 P15121 1/20 0.30
HPGD P15428 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7167552 0.81 L3MBTL1 (0.36) L3MBTL1MAPK1ALDH1A1LMNASMN1; SMN2
SCHEMBL7163601 0.79 LPL (0.35) L3MBTL1ALDH1A1LMNAMAPTGAA
SCHEMBL1158784 0.79 PTGDR (0.40) L3MBTL1ALDH1A1LMNAMAPTGAA
SCHEMBL1158972 0.79 LMNA (0.32) ALDH1A1LMNAMAPTGAAKDM4E
SCHEMBL7159511 0.78 ALDH1A1 (0.45) L3MBTL1ALDH1A1LMNASMN1; SMN2MAPT
SCHEMBL7161860 0.76 KDM4E (0.41) L3MBTL1ALDH1A1LMNASMN1; SMN2MAPT
SCHEMBL1159144 0.75 CA1 (0.41) ALDH1A1MAPTGAAKDM4EMEN1
SCHEMBL1426511 0.73 POLB (0.34) ALDH1A1LMNASMN1; SMN2MAPTGAA
SCHEMBL1159239 0.72 NR5A1 (0.40) LMNAMAPTGAATP53HPGD
SCHEMBL1158686 0.71 GABRA1 (0.37) ALDH1A1MAPTGAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811368-B1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORP (JP) 2003-07-23 EP disclosed
US-5866631-A POLYMERIZABLE MONOMER CONTAINING AN ACIDIC GROUP, WATER, ARYL BORATE AND TRANSITION METAL COMPOUND. TOKUYAMA CORPORATION (JP) 1999-02-02 US disclosed
EP-0811368-A1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORPORATION (JP) 1997-12-10 EP disclosed