SCHEMBL716663

SCHEMBL716663

CCOc1cc(N(CC)c2ccccc2)ccc1C1(c2c(C)n(CC)c3ccccc23)OC(=O)c2cccnc21

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
CYP3A4 P08684 1/20 0.33
TP53 P04637 2/20 0.33
THRB P10828 1/20 0.33
METAP2 P50579 1/20 0.32
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
ADORA2A P29274 1/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496970 1.00 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL25190560 0.93 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2CYP3A4LMNAHTT
SCHEMBL25187571 0.92 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL50771 0.91 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL29383067 0.91 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL30122739 0.91 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL3178659 0.91 CYP3A4 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL3191798 0.91 CYP3A4 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL3178341 0.90 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB
SCHEMBL3184517 0.90 CYP3A4 (0.35) ALDH1A1SMN1; SMN2CYP3A4TP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9939747-B2 Developing agent and method for producing the same TOSHIBA TEC KABUSHIKI KAISHA (JP) 2018-04-10 US claimed
US-20170038698-A1 DEVELOPING AGENT AND METHOD FOR PRODUCING THE SAME TOSHIBA TEC KABUSHIKI KAISHA (JP) 2017-02-09 US claimed
US-12575977-B2 Composition for wet indicator HENKEL AG & CO. KGAA (DE) 2026-03-17 US disclosed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
US-12497558-B2 Colour change composition and compounds THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-12-16 US disclosed
US-20250340748-A1 Ultraviolet Light Stable Color-Changing Systems CHROMATIC TECHNOLOGIES, INC. (US) 2025-11-06 US disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
US-12359083-B2 Ultraviolet light stable color-changing systems CHROMATIC TECHNOLOGIES, INC. (US) 2025-07-15 US disclosed
US-12297357-B2 Temperature-sensitive indicator THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-05-13 US disclosed
EP-0906311-A1 N-SULFONYLIMIDAZOLES USED AS FUNGICIDES BAYER AG (DE) 1999-04-07 EP disclosed
WO-1999010334-A1 ACYLATED 5-AMINOISOTHIAZOLES AS PESTICIDES AND FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-03-04 WO disclosed
WO-1999005149-A1 TRIAZOLINE-THION-PHOSPHORIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1999-02-04 WO disclosed
WO-1998047897-A1 SULFONYLOXADIAZOLONES AND THEIR USE AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-10-29 WO disclosed
EP-0873881-A1 Reversible thermochromic compositions The Pilot Ink CO., Ltd. (JP) 1998-10-28 EP disclosed
WO-1998039331-A1 ANNULATED AZOLE DERIVATIVES USEFUL AS MICROBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1998-09-11 WO disclosed
WO-1998021189-A1 HALOGEN PYRIMIDINYL ARYL (THIO)ETHERS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-05-22 WO disclosed
WO-1998016500-A1 HALOGENALKOXIMINOACETAMIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-04-23 WO disclosed
WO-1997047620-A1 N-SULFONYLIMIDAZOLES USED AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12297357-B2 Temperature-sensitive indicator NCS1, TREH, NEFM ALDH1A1 1168/4885SMN1; SMN2 1156/4885CYP3A4 849/4885
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB ALDH1A1 3835/4885SMN1; SMN2 2298/4885CYP3A4 1450/4885
US-12575977-B2 Composition for wet indicator HAO2, ALOX12, CD44 ALDH1A1 949/4885SMN1; SMN2 1843/4885CYP3A4 2205/4885
US-12497558-B2 Colour change composition and compounds C5, C9, C3AR1 ALDH1A1 1565/4885SMN1; SMN2 1751/4885CYP3A4 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.