Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136262 | 0.77 | PTAFR (0.43) | HRH1TSHRKCNH2 | |
| SCHEMBL9284701 | 0.77 | SIGMAR1 (0.42) | HRH1MEN1KMT2A | |
| Water SCHEMBL7140424 | 0.76 | PTAFR (0.40) | HRH1KCNH2PRMT5WDR77 | |
| SCHEMBL7140680 | 0.76 | PTAFR (0.40) | HRH1KCNH2 | |
| SCHEMBL7139726 | 0.75 | HRH1 (0.38) | HRH1KCNH2 | |
| SCHEMBL7141837 | 0.75 | HRH1 (0.50) | HRH1TSHRKCNH2MEN1KMT2A | |
| SCHEMBL7141253 | 0.74 | PTAFR (0.38) | HRH1KCNH2MEN1KMT2A | |
| Oxalic Acid SCHEMBL7138856 | 0.72 | HTR5A (0.49) | HRH1 | |
| Oxalic Acid SCHEMBL7143554 | 0.71 | LMNA (0.41) | HRH1TSHRCACNA1GKCNH2MEN1 | |
| Oxalic Acid SCHEMBL7143552 | 0.71 | LMNA (0.41) | HRH1TSHRCACNA1GKCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675887-B1 | ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-02 | — | — | EP | disclosed |