Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078065 | 0.92 | WRN (0.36) | L3MBTL1ALDH1A1WRNBACE1GAA | |
| SCHEMBL6301600 | 0.92 | KDM4E (0.34) | L3MBTL1KDM4EWRNGAA | |
| SCHEMBL6295721 | 0.89 | PPIB (0.32) | PPIB | |
| SCHEMBL6302130 | 0.86 | OPRM1 (0.32) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6297070 | 0.84 | CALM1 (0.37) | ALDH1A1CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL7081429 | 0.83 | TRPM8 (0.45) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL7078899 | 0.83 | WRN (0.34) | L3MBTL1ALDH1A1WRNGAA | |
| SCHEMBL6302378 | 0.83 | DRD2 (0.31) | — | |
| SCHEMBL6295768 | 0.82 | OPRD1 (0.34) | MAOBMAOAWRNBACE1 | |
| SCHEMBL6297241 | 0.82 | LMNA (0.34) | KDM4EWRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | claimed |