SCHEMBL7167443

SCHEMBL7167443

Cc1ccc(S(=O)(=O)Nc2ccc(N)c3c2-c2ccccc2-3)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.63
CYP2C9 P11712 2/20 0.63
CYP2C19 P33261 2/20 0.63
MAPT P10636 2/20 0.63
USP2 O75604 1/20 0.63
ALDH1A1 P00352 1/20 0.63
POLB P06746 1/20 0.63
NOD2 Q9HC29 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
KEAP1 Q14145 2/20 0.59
NFE2L2 Q16236 1/20 0.59
CA2 P00918 3/20 0.57
CA9 Q16790 3/20 0.57
CA12 O43570 2/20 0.57
MCOLN3 Q8TDD5 1/20 0.57
CDK2 P24941 1/20 0.54
CA1 P00915 2/20 0.51
CA4 P22748 1/20 0.51
CA7 P43166 1/20 0.51
EP300 Q09472 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846547 0.90 CDK2 (0.62) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL10488008 0.84 LMNA (0.54) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL9178476 0.83 LMNA (0.73) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL30238204 0.81 KEAP1 (0.61) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL19451108 0.79 LMNA (0.82) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL398000 0.79 LMNA (0.70) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL9171170 0.76 PGAM1 (0.67) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL9355616 0.76 LMNA (0.61) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL2068526 0.76 LMNA (0.82) LMNACYP2C9CYP2C19MAPTUSP2
SCHEMBL9172475 0.76 LMNA (0.71) LMNACYP2C9CYP2C19MAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1276802-A1 LIQUID STABILIZING MIXTURES FOR ORGANIC POLYMERS Great Lakes Chemical (Europe) GmbH (CH) 2003-01-22 EP disclosed
EP-1268633-A1 STABILIZING MIXTURES FOR ORGANIC POLYMERS Great Lakes Chemical (Europe) GmbH (CH) 2003-01-02 EP disclosed
WO-2001081458-A1 LIQUID STABILIZING MIXTURES FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2001-11-01 WO disclosed
WO-2001070868-A1 STABLILIZING MIXTURES FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2001-09-27 WO disclosed