Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178476 | 0.91 | LMNA (0.73) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9846547 | 0.83 | CDK2 (0.62) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9171170 | 0.83 | PGAM1 (0.67) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9355358 | 0.83 | LMNA (0.69) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11078073 | 0.82 | CDK2 (0.71) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9172475 | 0.81 | LMNA (0.71) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL13564135 | 0.78 | LMNA (0.73) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9303201 | 0.77 | KEAP1 (0.60) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9903086 | 0.77 | LMNA (0.70) | LMNAMAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7167443 | 0.76 | LMNA (0.63) | LMNAMAPTALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368750-B1 | Process for preparing substituted aminoanthraquinones | SUMITOMO CHEMICAL CO (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5017713-A | Alkylation | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0368750-A2 | Process for preparing substituted aminoanthraquinones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-16 | — | — | EP | disclosed |