SCHEMBL9846547

SCHEMBL9846547

Cc1ccc(S(=O)(=O)Nc2ccc(N)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.62
LMNA P02545 4/20 0.61
MAPT P10636 4/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP2C9 P11712 2/20 0.61
CYP2C19 P33261 2/20 0.61
USP2 O75604 1/20 0.61
POLB P06746 1/20 0.61
NOD2 Q9HC29 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
PGAM1 P18669 1/20 0.60
KEAP1 Q14145 1/20 0.57
NFE2L2 Q16236 1/20 0.57
CA2 P00918 3/20 0.56
CA9 Q16790 3/20 0.56
CA12 O43570 2/20 0.56
MCOLN3 Q8TDD5 1/20 0.56
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
HTT P42858 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9178476 0.91 LMNA (0.73) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL10488008 0.91 LMNA (0.54) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL7167443 0.90 LMNA (0.63) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL9171170 0.83 PGAM1 (0.67) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL9355616 0.83 LMNA (0.61) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL9355358 0.83 LMNA (0.69) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL11349106 0.82 MEN1 (0.54) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL9172475 0.81 LMNA (0.71) CDK2LMNAMAPTALDH1A1CYP2C9
SCHEMBL30238204 0.80 KEAP1 (0.61) LMNAMAPTALDH1A1CYP2C9CYP2C19
SCHEMBL10809232 0.80 P2RY4 (0.60) LMNAMAPTALDH1A1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107617393-A A kind of phosgene reactor for carbon tetrachloride processing equipment 徐州工程学院 2018-01-23 CN claimed
CN-107519748-A A kind of flash mixer 徐州工程学院 2017-12-29 CN claimed
CN-107651719-A A kind of carbon tetrachloride separator for groundwater treatment 徐州工程学院 2018-02-02 CN disclosed
CN-107617393-A A kind of phosgene reactor for carbon tetrachloride processing equipment 徐州工程学院 2018-01-23 CN disclosed
CN-107519748-A A kind of flash mixer 徐州工程学院 2017-12-29 CN disclosed
CN-106517865-A Coupling agent special for flexible macromolecular polymer bonding mortar and preparation method thereof 徐州工程学院 2017-03-22 CN disclosed
EP-0432095-A1 Anthraquino vat dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
EP-0274458-B1 ANTHRAQUINONE VAT DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-09-19 EP disclosed
EP-0274458-A1 Anthraquinone vat dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1988-07-13 EP disclosed
EP-0132757-B1 PROCESS FOR THE PREPARATION OF OXAMIDES BAYER AG (DE) 1986-09-24 EP disclosed
EP-0132757-A1 Process for the preparation of oxamides BAYER AG (DE) 1985-02-13 EP disclosed
EP-0019285-B1 PROCESS FOR PREPARING ASYMMETRICAL VAT DYESTUFFS OF THE ANTHRAQUINONE SERIES AND THEIR USE IN DYEING AND PRINTING CIBA-GEIGY AG (CH) 1984-05-09 EP disclosed
EP-0075173-A2 Anthraquinone dyes BAYER AG (DE) 1983-03-30 EP disclosed
US-4329456-A ACYLATION WITHOUT INTERMEDIATE ISOLATION CIBA-GEIGY AG (CH) 1982-05-11 US disclosed
US-4284770-A DEHALOGENATION, HYDRAZINE COMPOUND CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
EP-0019285-A1 Process for preparing asymmetrical vat dyestuffs of the anthraquinone series and their use in dyeing and printing CIBA-GEIGY AG (CH) 1980-11-26 EP disclosed
US-3972881-A VAT, CELLULOSE CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3935208-A NATURAL OR REGENERATED CELLULOSE ALTERMATT HANS 1976-01-27 US disclosed