Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | UQCRB | P14927 | 1/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720181 | 0.89 | HSD17B2 (0.71) | PKMHSD17B2KMT2AALDH1A1UQCRB | |
| SCHEMBL15045213 | 0.89 | KMT2A (0.71) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7173226 | 0.86 | ALDH1A1 (0.71) | HSD17B2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3259544 | 0.86 | HSD17B2 (0.72) | PKMHSD17B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2665022 | 0.83 | KMT2A (0.73) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3259769 | 0.83 | HSD17B2 (0.73) | PKMHSD17B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7181551 | 0.83 | HSD17B2 (0.67) | PKMHSD17B2KMT2AALDH1A1MAPT | |
| SCHEMBL1592806 | 0.83 | LMNA (0.60) | HSD17B2KMT2AMEN1ALDH1A1MAPT | |
| Phenol SCHEMBL11689536 | 0.82 | POLB (0.68) | PKMHSD17B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7178676 | 0.81 | PGR (0.71) | PKMHSD17B2ALDH1A1MAPTUQCRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |