SCHEMBL3259544

SCHEMBL3259544

Cc1ccc(S(=O)(=O)Nc2cccc(O)c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B2 P37059 4/20 0.72
▸ UQCRB P14927 1/20 0.71
▸ CA12 O43570 1/20 0.65
▸ CA1 P00915 1/20 0.65
▸ CA2 P00918 1/20 0.65
▸ CA9 Q16790 1/20 0.65
▸ CYTH2 Q99418 1/20 0.64
▸ TCF4 P15884 1/20 0.63
▸ CTNNB1 P35222 1/20 0.63
▸ FFAR1 O14842 1/20 0.62
▸ CDK1 P06493 1/20 0.62
▸ CCNB1 P14635 1/20 0.62
▸ CCNA2 P20248 1/20 0.62
▸ CDK2 P24941 1/20 0.62
▸ CDK7 P50613 1/20 0.62
▸ CCNH P51946 1/20 0.62
▸ CCNA1 P78396 1/20 0.62
▸ FFAR4 Q5NUL3 1/20 0.62
▸ KMT2A Q03164 2/20 0.62
▸ HSD17B1 P14061 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1592342 0.88 HSD17B2 (0.79) HSD17B2UQCRBFFAR4KMT2AHSD17B1
SCHEMBL14877794 0.88 CA12 (0.76) CA12CA1CA2CA9TCF4
SCHEMBL7170802 0.86 PKM (0.62) HSD17B2UQCRBKMT2AHSD17B1GAA
SCHEMBL3259769 0.85 HSD17B2 (0.73) HSD17B2UQCRBCYTH2KMT2AHSD17B1
SCHEMBL7176831 0.85 CYTH2 (0.70) CA12CA1CA2CA9CYTH2
SCHEMBL3701951 0.85 CA12 (0.71) CA12CA1CA2CA9TCF4
SCHEMBL7181551 0.84 HSD17B2 (0.67) HSD17B2UQCRBKMT2AHSD17B1GAA
SCHEMBL6302356 0.84 CYP19A1 (0.78) HSD17B2UQCRBKMT2AHSD17B1GAA
SCHEMBL8864887 0.84 HTR6 (0.73) HSD17B2UQCRBCA1CA2CA9
SCHEMBL1592806 0.84 LMNA (0.60) HSD17B2UQCRBCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020061819-A1 Heat-sensitive recording material OJI PAPER CO., LTD. (JP) 2002-05-23 — — US claimed
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 — — EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 — — US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 — — EP claimed
US-9834022-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2017-12-05 — — US disclosed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 — — EP disclosed
US-20160332469-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2016-11-17 — — US disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 — — EP disclosed
US-9028562-B2 Dye composition using a 2-hydroxynaphthalene, (acylamino)phenol or quinoline coupler in a fatty-substance-rich medium, dyeing process and device therefor L'OREAL (FR) 2015-05-12 — — US disclosed
US-9028562-B2 Dye composition using a 2-hydroxynaphthalene, (acylamino)phenol or quinoline coupler in a fatty-substance-rich medium, dyeing process and device therefor L'OREAL (FR) 2015-05-12 — — US disclosed
EP-2096149-B1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED MITSUBISHI PAPER MILLS LTD (JP) 2014-10-22 — — EP disclosed
US-20140041133-A1 DYE COMPOSITION USING A 2-HYDROXYNAPHTHALENE, (ACYLAMINO)PHENOL OR QUINOLINE COUPLER IN A FATTY-SUBSTANCE-RICH MEDIUM, DYEING PROCESS AND DEVICE THEREFOR L'OREAL (FR) 2014-02-13 — — US disclosed
US-6579829-B2 Aromatic sulfonamide compound MITSUI CHEMICALS, INC. (JP) 2003-06-17 — — US disclosed
WO-2002078970-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 — — WO disclosed
US-20020061819-A1 Heat-sensitive recording material OJI PAPER CO., LTD. (JP) 2002-05-23 — — US disclosed
US-20020061819-A1 Heat-sensitive recording material OJI PAPER CO., LTD. (JP) 2002-05-23 — — US disclosed
WO-2002014081-A1 THERMAL RECORDING MATERIAL OJI PAPER CO., LTD. (JP) 2002-02-21 — — WO disclosed
EP-1138517-A2 Developer composition and heat sensitive recording material Mitsui Chemicals, Inc. (JP) 2001-10-04 — — EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 — — EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140041133-A1 DYE COMPOSITION USING A 2-HYDROXYNAPHTHALENE, (ACYLAMINO)PHENOL OR QUINOLINE COUPLER IN A FATTY-SUBSTANCE-RICH MEDIUM, DYEING PROCESS AND DEVICE THEREFOR HADHB, HADH, FABP4 HSD17B2 192/4885UQCRB 480/4885CA12 1642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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