SCHEMBL3259769

SCHEMBL3259769

O=S(=O)(Nc1cccc(O)c1)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 4/20 0.73
KMT2A Q03164 2/20 0.71
UQCRB P14927 1/20 0.68
IL1RN P18510 1/20 0.66
KEAP1 Q14145 1/20 0.66
ERAP1 Q9NZ08 1/20 0.66
HTR6 P50406 3/20 0.65
PKM P14618 2/20 0.64
MEN1 O00255 1/20 0.61
ALDH1A1 P00352 1/20 0.61
GAA P10253 2/20 0.61
GFER P55789 1/20 0.61
APOBEC3G Q9HC16 1/20 0.61
CYTH2 Q99418 2/20 0.60
HPGD P15428 1/20 0.59
HSD17B1 P14061 2/20 0.57
LMNA P02545 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
PGR P06401 1/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16720181 0.91 HSD17B2 (0.71) HSD17B2KMT2AUQCRBIL1RNKEAP1
SCHEMBL6297524 0.90 HSD17B2 (0.70) HSD17B2KMT2AUQCRBIL1RNKEAP1
SCHEMBL16719342 0.89 IL1RN (0.66) HSD17B2KMT2AUQCRBIL1RNKEAP1
SCHEMBL1592342 0.89 HSD17B2 (0.79) HSD17B2KMT2AUQCRBHTR6PKM
SCHEMBL9001184 0.87 KEAP1 (0.79) KMT2AIL1RNKEAP1ERAP1HTR6
SCHEMBL6302122 0.86 HSD17B2 (0.65) HSD17B2KMT2AUQCRBHTR6PKM
SCHEMBL7180209 0.85 CYTH2 (0.67) HSD17B2KMT2AUQCRBIL1RNKEAP1
SCHEMBL3259544 0.85 HSD17B2 (0.72) HSD17B2KMT2AUQCRBPKMMEN1
SCHEMBL8864887 0.85 HTR6 (0.73) HSD17B2KMT2AUQCRBKEAP1HTR6
SCHEMBL6302356 0.85 CYP19A1 (0.78) HSD17B2KMT2AUQCRBPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105939867-B Thermal recording medium 三菱制纸株式会社 2018-05-11 CN disclosed
US-9834022-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2017-12-05 US disclosed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 EP disclosed
US-20160332469-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2016-11-17 US disclosed
CN-105939867-A Heat-sensitive recording material 三菱制纸株式会社 2016-09-14 CN disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 EP disclosed
EP-2096149-B1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED MITSUBISHI PAPER MILLS LTD (JP) 2014-10-22 EP disclosed
US-8288313-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-16 US disclosed
US-8283285-B2 Scratch color-developable ink and invisible information printed sheet MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-09 US disclosed
US-20100069240-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2010-03-18 US disclosed
WO-2005034960-A1 TREATMENT OF DISEASES ASSOCIATED WITH THE EGR-1 ENHANCER ELEMENT RESVERLOGIX CORP. (CA) 2005-04-21 WO disclosed
US-20050080024-A1 Nitric oxide donating derivatives for the treatment of cardiovascular disorders RESVERLOGIX CORP. (CA) 2005-04-14 US disclosed
US-20050080021-A1 Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders RESVERLOGIX CORP. (CA) 2005-04-14 US disclosed
WO-2005032559-A1 NITRIC OXIDE DONATING DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS RESVERLOGIX CORP. (CA) 2005-04-14 WO disclosed
US-6579829-B2 Aromatic sulfonamide compound MITSUI CHEMICALS, INC. (JP) 2003-06-17 US disclosed
WO-2002078970-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
EP-1138517-A2 Developer composition and heat sensitive recording material Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed
EP-0125522-B1 COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1989-01-11 EP disclosed
US-4530899-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1985-07-23 US disclosed
EP-0125522-A2 Color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1984-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080024-A1 Nitric oxide donating derivatives for the treatment of cardiovascular disorders NOS2, NOS3, NOS1 HSD17B2 178/4885KMT2A 2695/4885UQCRB 1114/4885
US-20050080021-A1 Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders NOS2, NOS1, NOS3 HSD17B2 167/4885KMT2A 2279/4885UQCRB 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.