Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | UQCRB | P14927 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719693 | 0.94 | MAPT (0.61) | PKMHSD17B2HSD17B1MAPTPOLB | |
| SCHEMBL16720181 | 0.89 | HSD17B2 (0.71) | PKMHSD17B2HSD17B1POLBUQCRB | |
| SCHEMBL7177694 | 0.86 | PGR (0.65) | PKMMAPTPOLBUQCRBKMT2A | |
| SCHEMBL7175051 | 0.86 | HSD17B2 (0.72) | PKMHSD17B2HSD17B1UQCRBKMT2A | |
| SCHEMBL3259769 | 0.83 | HSD17B2 (0.73) | PKMHSD17B2HSD17B1POLBUQCRB | |
| SCHEMBL7170802 | 0.81 | PKM (0.62) | PKMHSD17B2HSD17B1MAPTUQCRB | |
| SCHEMBL7178676 | 0.81 | PGR (0.71) | PKMHSD17B2HSD17B1MAPTUQCRB | |
| SCHEMBL30737540 | 0.81 | HTR6 (0.71) | PKMMAPTPOLBKMT2APGR | |
| SCHEMBL28271830 | 0.81 | HTR6 (0.71) | PKMMAPTPOLBKMT2APGR | |
| SCHEMBL3724198 | 0.81 | THRB (0.79) | MAPTPOLBKMT2ATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |