Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701104 | 0.79 | LMNA (0.57) | MAPTLMNACES1ALDH1A1ACHE | |
| SCHEMBL6423919 | 0.73 | CA1 (0.67) | APPMAPTLMNACES1CA12 | |
| SCHEMBL28198 | 0.73 | CA1 (0.67) | APPMAPTLMNACES1CA12 | |
| Water SCHEMBL28670631 | 0.71 | CA1 (0.64) | APPMAPTLMNACES1CA12 | |
| SCHEMBL28711861 | 0.71 | ALDH1A1 (0.65) | APPLMNACES1CA12CA1 | |
| SCHEMBL27909482 | 0.71 | ALDH1A1 (0.72) | APPLMNACES1CA12CA1 | |
| SCHEMBL22567 | 0.71 | ALDH1A1 (0.72) | APPLMNACES1CA12CA1 | |
| SCHEMBL15329437 | 0.69 | HSPB1 (0.51) | MAPTLMNACES1CA1CA2 | |
| SCHEMBL27543846 | 0.69 | CYP19A1 (0.68) | LMNACES1CA12CA1CA2 | |
| SCHEMBL29769219 | 0.69 | XDH (0.58) | APPMAPTLMNACES1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010053855-A1 | Oligonucleotide protecting groups | ISIS PHARMACEUTICALS, INC. | 2001-12-20 | — | — | US | claimed |
| WO-2000014048-A1 | OLIGONUCLEOTIDE PROTECTING GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | claimed |
| US-6576783-B2 | Modified alkoxycarbonyloxypyridine as oligonucleotide blocking agent | ISIS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
| US-20010053855-A1 | Oligonucleotide protecting groups | ISIS PHARMACEUTICALS, INC. | 2001-12-20 | — | — | US | disclosed |
| US-6166239-A | Oligonucleotide protecting groups | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000014048-A1 | OLIGONUCLEOTIDE PROTECTING GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053855-A1 | Oligonucleotide protecting groups | RNGTT, APEX1, OGG1 | APP 4332/4885MAPT 4376/4885LMNA 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.