Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | QDPR | P09417 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7617662 | 0.98 | SLC18A3 (0.55) | SLC18A3SIGMAR1HTR2CP2RY14QDPR | |
| SCHEMBL12489074 | 0.93 | DRD2 (0.51) | SLC18A3SIGMAR1HTR2CP2RY14QDPR | |
| SCHEMBL14862100 | 0.88 | HTR3A (0.61) | SLC18A3SIGMAR1JAK3HTR3A | |
| SCHEMBL5958188 | 0.87 | GRIA1 (0.49) | GRIA1GRIA2GRIA3 | |
| Hydrochloric Acid SCHEMBL29051119 | 0.86 | HTR3A (0.59) | SLC18A3SIGMAR1HTR2CJAK3HTR3A | |
| SCHEMBL3124665 | 0.83 | SLC18A3 (0.49) | SLC18A3SIGMAR1HTR2CP2RY14JAK2 | |
| SCHEMBL250894 | 0.83 | MAOA (0.50) | GRIA1GRIA2GRIA3 | |
| SCHEMBL3706669 | 0.83 | KCNH2 (0.46) | GRIA1GRIA2GRIA3 | |
| SCHEMBL16156071 | 0.82 | SLC6A2 (0.56) | SLC18A3SIGMAR1HTR2CP2RY14QDPR | |
| Tert-Butyl Formate SCHEMBL28096208 | 0.82 | HTR2C (0.42) | SLC18A3SIGMAR1HTR2CP2RY14QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768826-B | Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-05-27 | — | — | CN | claimed |
| CN-116768826-A | Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2023-09-19 | — | — | CN | claimed |
| EP-4722204-A1 | INDUSTRIAL PREPARATION OF HETEROCYCLIC MODULATOR FOR LIPID SYNTHESIS | Sagimet Biosciences Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12551490-B2 | Heterocyclic modulators of lipid synthesis | SAGIMET BIOSCIENCES INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-12478621-B2 | Substituted aminoquinolones as dgkalpha inhibitors for immune activation | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2025-11-25 | — | — | US | disclosed |
| CN-116768826-B | Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-05-27 | — | — | CN | disclosed |
| CN-119798161-A | Preparation method of plant growth regulating substance and multiple uses thereof | 贵州工业职业技术学院 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024251076-A1 | INDUSTRIAL PREPARATION OF HETEROCYCLIC MODULATOR FOR LIPID SYNTHESIS | 甘莱制药有限公司 | 2024-12-12 | — | — | WO | disclosed |
| CN-119080742-A | Industrial preparation of heterocyclic modulators of lipid synthesis | 甘莱制药有限公司 | 2024-12-06 | — | — | CN | disclosed |
| US-20240400552-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | SAGIMET BIOSCIENCES INC. | 2024-12-05 | — | — | US | disclosed |
| CN-112996513-B | Novel pyridazines | 勃林格殷格翰国际有限公司 | 2024-10-15 | — | — | CN | disclosed |
| EP-0609282-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-10 | — | — | EP | disclosed |
| CN-1090273-A | Acetogenin | GLAXO GROUP LTD (GB) | 1994-08-03 | — | — | CN | disclosed |
| CN-1087904-A | Carboxylic acid derivative, the pharmaceutical composition that contains these compounds with and preparation method thereof | KRAL THOMAE GMBH (DE) | 1994-06-15 | — | — | CN | disclosed |
| EP-0592949-A2 | N-(aminocarbonyl)-piperidines/pepirazines as aggregation inhibiting agents | Dr. Karl Thomae GmbH (DE) | 1994-04-20 | — | — | EP | disclosed |
| CN-1073433-A | Cyclohexaneacetic acid derivatives | GLAXO GROUP LTD (GB) | 1993-06-23 | — | — | CN | disclosed |
| CN-1073169-A | Acetogenin | GLAXO GROUP LTD (GB) | 1993-06-16 | — | — | CN | disclosed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993008181-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12478621-B2 | Substituted aminoquinolones as dgkalpha inhibitors for immune activation | DGKK, DGKG, DGKA | SLC18A3 4364/4885SIGMAR1 4076/4885HTR2C 4530/4885 |
| US-20240400552-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | FASN, FADS1, FADS2 | SLC18A3 3612/4885SIGMAR1 2852/4885HTR2C 2768/4885 |
| US-12551490-B2 | Heterocyclic modulators of lipid synthesis | FASN, FADS1, FADS2 | SLC18A3 3758/4885SIGMAR1 348/4885HTR2C 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.