Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526972 | 1.00 | TSHR (0.44) | TSHRMGLLHRH3ALDH1A1CA12 | |
| SCHEMBL1582709 | 1.00 | TSHR (0.44) | TSHRMGLLHRH3ALDH1A1CA12 | |
| Hydrochloric Acid SCHEMBL28974479 | 0.97 | TSHR (0.42) | TSHRMGLLHRH3ALDH1A1CA12 | |
| SCHEMBL170249 | 0.97 | TSHR (0.40) | TSHRMGLLHRH3ALDH1A1CA12 | |
| SCHEMBL6300105 | 0.90 | TSHR (0.43) | TSHRMGLLALDH1A1CA12CA7 | |
| SCHEMBL31348042 | 0.87 | ALDH1A1 (0.44) | TSHRMGLLALDH1A1CA12CA7 | |
| SCHEMBL236146 | 0.86 | MGLL (0.47) | TSHRMGLLALDH1A1CA12CA7 | |
| SCHEMBL5866410 | 0.85 | TSHR (0.34) | TSHR | |
| SCHEMBL19878897 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28019904 | 0.82 | MGLL (0.44) | TSHRMGLLALDH1A1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049760-A1 | CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | claimed |
| EP-4178576-A1 | DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS | Emergent Product Development Gaithersburg Inc. (US) | 2023-05-17 | — | — | EP | claimed |
| CN-115260234-A | 2-amino-4-amino aryl phospho-oxypyrimidine compound and preparation method and application thereof | 江苏医药职业学院 | 2022-11-01 | — | — | CN | claimed |
| CN-114105908-A | Preparation method of key intermediate of tetrahydronaphthalene benzamide | 辽宁大学 | 2022-03-01 | — | — | CN | claimed |
| US-20210253575-A1 | PYRROLIDINE AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2021-08-19 | — | — | US | claimed |
| EP-3847165-A1 | NOVEL PYRROLIDINE AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2021-07-14 | — | — | EP | claimed |
| CN-112673003-A | Novel pyrrolidine amine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2021-04-16 | — | — | CN | claimed |
| CN-112384068-A | Use of a combination of a fungicide and glycine betaine for controlling fungal plant pathogens | 丹斯塔发酵股份公司 | 2021-02-19 | — | — | CN | claimed |
| CN-109021221-B | Novel composite catalyst for synthesizing polycarbonate by melting method | 北京濮源新材料技术研究院(普通合伙) | 2020-09-01 | — | — | CN | claimed |
| CN-110372703-A | Five-ring heterocycles miazines compound and application thereof | 罗欣生物科技（上海）有限公司 | 2019-10-25 | — | — | CN | claimed |
| US-4940783-A | Disazo containing diaminostilbene as diazo component and an aniline coupling component bearing a cationic alkyl ammonium group | CIBA-GEIGY CORPORATION (US) | 1990-07-10 | — | — | US | claimed |
| EP-0342682-A2 | Hydroxamate derivatives of selected nonsteroidal anti-inflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition | WARNER-LAMBERT COMPANY (US) | 1989-11-23 | — | — | EP | claimed |
| US-4839358-A | ANALGESICS, ANTIDEPRESSANTS, ANTIANXIETY AGENTS | ROUSSEL UCLAF (FR) | 1989-06-13 | — | — | US | claimed |
| US-4816571-A | Chemical capping by phosphitylation during oligonucleotide synthesis | APPLIED BIOSYSTEMS, INC. (US) | 1989-03-28 | — | — | US | claimed |
| EP-0251937-A1 | Tricyclic agonist derivatives of cholinergic receptors, and medicines containing them | SANOFI (FR) | 1988-01-07 | — | — | EP | claimed |
| US-4695632-A | ANIONIC DYE AFFINITY | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | claimed |
| EP-0060468-B1 | PROCESS FOR THE DYEING OF PAPER AND DYED PAPER | BAYER AG (DE) | 1984-10-03 | — | — | EP | claimed |
| US-4471417-A | LIGHT STABILIZERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | claimed |
| EP-0031266-B1 | 1-AMINO-2-PROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTIC USE | ELF SANOFI (FR) | 1983-02-09 | — | — | EP | claimed |
| US-4362874-A | PYRIMIDINES, ANIONIC DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253575-A1 | PYRROLIDINE AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | ARG1, PRMT1, PADI1 | TSHR 119/4885MGLL 4815/4885HRH3 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.