Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526972 | 1.00 | TSHR (0.44) | TSHRMGLLHRH3ALDH1A1CA12 | |
| SCHEMBL718510 | 1.00 | TSHR (0.44) | TSHRMGLLHRH3ALDH1A1CA12 | |
| Hydrochloric Acid SCHEMBL28974479 | 0.97 | TSHR (0.42) | TSHRMGLLHRH3ALDH1A1CA12 | |
| SCHEMBL170249 | 0.97 | TSHR (0.40) | TSHRMGLLHRH3ALDH1A1CA12 | |
| SCHEMBL6300105 | 0.90 | TSHR (0.43) | TSHRMGLLALDH1A1CA12CA7 | |
| SCHEMBL31348042 | 0.87 | ALDH1A1 (0.44) | TSHRMGLLALDH1A1CA12CA7 | |
| SCHEMBL236146 | 0.86 | MGLL (0.47) | TSHRMGLLALDH1A1CA12CA7 | |
| SCHEMBL5866410 | 0.85 | TSHR (0.34) | TSHR | |
| SCHEMBL19878897 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28019904 | 0.82 | MGLL (0.44) | TSHRMGLLALDH1A1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4815429-B2 | — | — | 2011-11-16 | — | — | JP | claimed |
| EP-1723203-B1 | VIOLET COLORANT FOR COLOUR FILTERS, INKS FOR INK-JET, ELECTROPHOTOGRAPHIC TONERS AND DEVELOPERS AND E-INKS | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-1723203-A1 | VIOLET COLORANT FOR COLOUR FILTERS, INKS FOR INK-JET, ELECTROPHOTOGRAPHIC TONERS AND DEVELOPERS AND E-INKS | Clariant Produkte (Deutschland) GmbH (DE) | 2006-11-22 | — | — | EP | claimed |
| WO-2005085367-A1 | VIOLET COLORANT FOR COLOUR FILTERS, INKS FOR INK-JET, ELECTROPHOTOGRAPHIC TONERS AND DEVELOPERS AND E-INKS | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2005-09-15 | — | — | WO | claimed |
| EP-0024582-A1 | Benzodiazepinones, process for their preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-11 | — | — | EP | claimed |
| US-8383666-B2 | Pyrrole derivatives, preparation of same and therapeutic application thereof | SANOFI (FR) | 2013-02-26 | — | — | US | disclosed |
| US-20110144157-A1 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | US | disclosed |
| US-20070248624-A1 | (1,10B-Dihydro-2-(Aminocarbonyl-Phenyl)-5h-Pyrazolo[1,5-C][1,3]Benzoxazin-5-Yl)Phenyl Methanone Derivatives as Hiv Viral Replication Inhibitors | JANSSEN SCIENCES IRELAND UC (IE) | 2007-10-25 | — | — | US | disclosed |
| CN-1040874-C | Triazolopyridazine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-11-25 | — | — | CN | disclosed |
| CN-1077958-A | The preparation of triazolopyridazine compounds, their and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144157-A1 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | ARG2, PYCR1, ARG1 | TSHR 763/4885MGLL 4528/4885HRH3 538/4885 |
| US-20070248624-A1 | (1,10B-Dihydro-2-(Aminocarbonyl-Phenyl)-5h-Pyrazolo[1,5-C][1,3]Benzoxazin-5-Yl)Phenyl Methanone Derivatives as Hiv Viral Replication Inhibitors | POLRMT, MAVS, DHX15 | TSHR 4879/4885MGLL 2805/4885HRH3 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.