Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484855 | 0.87 | TSHR (0.36) | CNR1CNR2KCNH2TSHRKMT2A | |
| SCHEMBL5680093 | 0.87 | TSHR (0.41) | KCNH2TSHRKMT2AAPPBACE1 | |
| SCHEMBL20414593 | 0.73 | L3MBTL1 (0.51) | TSHRMEN1CYP3A4KMT2AMCHR1 | |
| SCHEMBL19612195 | 0.72 | TLR8 (0.43) | CNR1CNR2KCNH2CYP2C9TSHR | |
| SCHEMBL28698562 | 0.72 | CNR1 (0.47) | CNR1CNR2CYP2C9MEN1CYP3A4 | |
| SCHEMBL27603617 | 0.72 | CNR1 (0.41) | CNR1CNR2CYP2C9TSHRCYP1A2 | |
| SCHEMBL7712652 | 0.71 | MAPT (0.46) | TSHRCYP1A2CYP2A6MEN1TP53 | |
| SCHEMBL28371895 | 0.71 | HTR1B (0.46) | CNR1CNR2CYP2C9MCHR1TLR8 | |
| SCHEMBL20678383 | 0.71 | MCHR1 (0.47) | CNR1CNR2KCNH2CYP2C9TSHR | |
| SCHEMBL600606 | 0.71 | LTA4H (0.52) | CNR1CNR2CYP2C9TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596774-B1 | For their ability to inhibit the growth of human oral epidermoid carcinoma cells, human cervical carcinoma cells and Chinese hamster ovary cells | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-22 | — | — | US | disclosed |
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-17 | — | — | US | disclosed |
| US-6369246-B2 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS | DR. KEITH CHAN, GLOBOASIA, LLC | 2002-04-09 | — | — | US | disclosed |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | CHAN, KEITH | 2001-08-30 | — | — | US | disclosed |
| WO-2000061536-A3 | SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS | GLOBOASIA L L C (US) | 2001-04-26 | — | — | WO | disclosed |
| WO-2000061536-A2 | SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS | GLOBOASIA, L.L.C. (US) | 2000-10-19 | — | — | WO | disclosed |
| WO-2000061536-A2 | SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS | GLOBOASIA, L.L.C. (US) | 2000-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | GPX4, GPX1, AGK | CNR1 1223/4885CNR2 2275/4885KCNH2 2329/4885 |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | C3AR1, C5AR2, TLR2 | CNR1 102/4885CNR2 47/4885KCNH2 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.