Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187367 | 0.98 | KMT2A (0.42) | L3MBTL1SMN1; SMN2KMT2APOLBPKM | |
| SCHEMBL8965109 | 0.78 | TSHR (0.49) | L3MBTL1SMN1; SMN2KMT2APOLBPKM | |
| SCHEMBL7699172 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL2835326 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27918598 | 0.75 | KMT2A (0.49) | L3MBTL1KMT2APOLBPKMPTPN1 | |
| SCHEMBL15142435 | 0.73 | KMT2A (0.50) | L3MBTL1KMT2APOLBPKMPTPN1 | |
| SCHEMBL6129965 | 0.73 | KMT2A (0.46) | L3MBTL1KMT2APOLBPKMPTPN1 | |
| SCHEMBL10762043 | 0.73 | L3MBTL1 (0.36) | L3MBTL1SMN1; SMN2KMT2APOLBPKM | |
| SCHEMBL7697891 | 0.71 | ALOX5 (0.43) | L3MBTL1KMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL1969808 | 0.70 | KMT2A (0.44) | L3MBTL1KMT2APOLBPKMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5493047-A | REACTING OPTICALLY ACTIVE CYANOHYDRIN WITH CARBOXYLIC ACID IN PRESENCE OF DIALKYL AZODICARBOXYLATE AND TRIPHENYLPHOSPHINE TO FORM ESTER OF OPPOSITE CONFIGURATION | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1996-02-20 | — | — | US | disclosed |
| EP-0601632-A1 | Method of preparing optically active cyanohydrin derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1994-06-15 | — | — | EP | disclosed |