Sugi Predict

Sugi Predict / Compounds / SCHEMBL718780

SCHEMBL718780

SCHEMBL718780

C=C(C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.51
▸ CA12 O43570 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA9 Q16790 1/20 0.47
▸ SLC7A5 Q01650 1/20 0.45
▸ OPRM1 P35372 1/20 0.45
▸ OPRD1 P41143 1/20 0.45
▸ FOLH1 Q04609 1/20 0.45
▸ MMP9 P14780 1/20 0.44
▸ MMP8 P22894 1/20 0.44
▸ PTPN2 P17706 1/20 0.44
▸ PTPN1 P18031 1/20 0.44
▸ HPGDS O60760 2/20 0.43
▸ ESR1 P03372 1/20 0.43
▸ ESR2 Q92731 1/20 0.43
▸ GRIA1 P42261 1/20 0.43
▸ PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346687 0.87 FOLH1 (0.59) ACECA1SLC7A5FOLH1MMP9
SCHEMBL8021425 0.87 FOLH1 (0.59) ACECA1SLC7A5FOLH1MMP9
SCHEMBL8374049 0.87 FCER2 (0.50) CA12CA1CA9MMP9MMP8
SCHEMBL468899 0.84 ACE (0.55) ACECA12CA1CA9SLC7A5
SCHEMBL6518708 0.84 ACE (0.55) ACECA12CA1CA9SLC7A5
SCHEMBL8842469 0.84 ACE (0.52) ACECA12CA1CA9SLC7A5
SCHEMBL23859819 0.84 NPSR1 (0.56) ESR1ESR2
SCHEMBL21117405 0.84 MMP9 (0.55) ACEFOLH1MMP9MMP8ESR1
SCHEMBL23859822 0.84 NPSR1 (0.56) ESR1ESR2
SCHEMBL15947340 0.82 BACE1 (0.47) ACEFOLH1MMP9MMP8ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7300428-A — — None — — JP disclosed
US-10406111-B2 Gold/lanthanide nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2019-09-10 — — US disclosed
US-9382346-B2 Gold nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2016-07-05 — — US disclosed
WO-2016082808-A1 ORAL PREPARATION USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I. (CZ) 2016-06-02 — — WO disclosed
US-20160017065-A1 Gold Nanoparticle Conjugates and Uses Thereof COLORADO SCHOOL OF MINES 2016-01-21 — — US disclosed
US-9175015-B2 Gold nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2015-11-03 — — US disclosed
US-20150306256-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2015-10-29 — — US disclosed
US-20150258034-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES 2015-09-17 — — US disclosed
US-20150250902-A1 pH-RESPONSIVE GADOLINIUM NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES (US) 2015-09-10 — — US disclosed
US-8968705-B2 Gold/lanthanide nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2015-03-03 — — US disclosed
EP-0941123-A2 DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS SCHACHT, Etienne Honoré (BE) 1999-09-15 — — EP disclosed
US-5883211-A Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis ACLARA BIOSCIENCES, INC. (US) 1999-03-16 — — US disclosed
WO-1998019710-A2 DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS SCHACHT ETIENNE HONORE (BE) 1998-05-14 — — WO disclosed
WO-1997040078-A1 THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS SOANE BIOSCIENCES (US) 1997-10-30 — — WO disclosed
JP-H07300428-A SYNTHETIC POLYMERIC DRUG CESKOSLOVENSKA AKAD VED 1995-11-14 — — JP disclosed
EP-0394400-B1 POLYMER SUPERSURFACTANTS FOR PROTEIN RESISTANCE AND PROTEIN REMOVAL UNIV UTAH (US) 1995-07-12 — — EP disclosed
EP-0394400-A4 POLYMER SUPERSURFACTANTS FOR PROTEIN RESISTANCE AND PROTEIN REMOVAL — 1991-12-27 — — EP disclosed
US-5075400-A Water soluble polymers with polyethylene oxide sidechains; adsorbed on hydrophobic surfaces UNIVERSITY OF UTAH (US) 1991-12-24 — — US disclosed
EP-0394400-A1 POLYMER SUPERSURFACTANTS FOR PROTEIN RESISTANCE AND PROTEIN REMOVAL. UNIV UTAH (US) 1990-10-31 — — EP disclosed
WO-1990003406-A1 POLYMER SUPERSURFACTANTS FOR PROTEIN RESISTANCE AND PROTEIN REMOVAL UNIVERSITY OF UTAH (US) 1990-04-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150306256-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof SSB, CD47, SLC6A13 ACE 2911/4885CA12 53/4885CA1 360/4885
US-20150258034-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF SSB, LGALS9, LGALS3 ACE 2712/4885CA12 70/4885CA1 665/4885
US-10406111-B2 Gold/lanthanide nanoparticle conjugates and uses thereof SSB, LGALS9, LGALS3 ACE 2712/4885CA12 70/4885CA1 665/4885
US-20150250902-A1 pH-RESPONSIVE GADOLINIUM NANOPARTICLE CONJUGATES AND USES THEREOF GOLGA3, GDI1, CA13 ACE 3986/4885CA12 11/4885CA1 54/4885
US-20160017065-A1 Gold Nanoparticle Conjugates and Uses Thereof CD47, SELP, SELPLG ACE 4059/4885CA12 296/4885CA1 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.