Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934720 | 0.82 | AOC3 (0.37) | ALDH1A1TSHRTDP1HPGDMAPT | |
| SCHEMBL15988650 | 0.79 | TSHR (0.39) | ALDH1A1TSHRTDP1ALOX15HPGD | |
| SCHEMBL1275601 | 0.78 | GABRA1 (0.42) | ALDH1A1TSHRTDP1ALOX15HPGD | |
| SCHEMBL16710910 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1ALOX15HPGD | |
| SCHEMBL30821022 | 0.77 | KIF11 (0.38) | ALDH1A1TSHRTDP1ALOX15HPGD | |
| SCHEMBL3542339 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1ALOX15HPGD | |
| SCHEMBL29788344 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1ALOX15HPGD | |
| SCHEMBL7930508 | 0.73 | ACHE (0.43) | ALDH1A1TSHRTDP1CA2CYP3A4 | |
| SCHEMBL7189127 | 0.73 | CETP (0.34) | ALDH1A1HPGDCA2CA12CA4 | |
| SCHEMBL5050103 | 0.73 | ENPP2 (0.39) | MAPTCA4CA5ACA14CA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220660-B1 | SEMI-PERMEABLES MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS | THE DOW CHEMICAL COMPANY (US) | 1992-03-11 | — | — | EP | claimed |
| US-4704324-A | REVERSE OSMOSIS, GAS SEPARATION, ULTRAFILTRATION | THE DOW CHEMICAL COMPANY (US) | 1987-11-03 | — | — | US | claimed |
| WO-1987002682-A1 | SEMI-PERMEABLE MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS | THE DOW CHEMICAL COMPANY (US) | 1987-05-07 | — | — | WO | claimed |
| EP-0220660-A2 | Semi-permeables membranes prepared via reaction of cationic groups with nucleophilic groups | THE DOW CHEMICAL COMPANY (US) | 1987-05-06 | — | — | EP | claimed |
| US-10927076-B2 | HSP90B N-terminal isoform-selective inhibitors | UNIVERSITY OF KANSAS (US) | 2021-02-23 | — | — | US | disclosed |
| US-6627714-B2 | Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| CN-1097588-C | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | UNIV FANDBILT (US) | 2003-01-01 | — | — | CN | disclosed |
| US-20020058767-A1 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1205497-A2 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| CN-1210529-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | PROCTER & GAMBLE (US) | 1999-03-10 | — | — | CN | disclosed |
| EP-0220660-B1 | SEMI-PERMEABLES MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS | THE DOW CHEMICAL COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0253985-B1 | STABILIZED MOULDING COMPOSITIONS BASED ON POLYVINYL CHLORIDE OR VINYL CHLORIDE COPOLYMERS AND STABILIZER SYSTEM | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-12-27 | — | — | EP | disclosed |
| US-4839203-A | COVALENT BONDING PRODUCING A COMPOSITE | THE DOW CHEMICAL COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| US-4797187-A | COACERVATION OF CATIONS | THE DOW CHEMICAL COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0253985-A2 | Stabilized moulding compositions based on polyvinyl chloride or vinyl chloride copolymers and stabilizer system | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-01-27 | — | — | EP | disclosed |
| US-4704324-A | REVERSE OSMOSIS, GAS SEPARATION, ULTRAFILTRATION | THE DOW CHEMICAL COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| WO-1987002682-A1 | SEMI-PERMEABLE MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS | THE DOW CHEMICAL COMPANY (US) | 1987-05-07 | — | — | WO | disclosed |
| EP-0220660-A2 | Semi-permeables membranes prepared via reaction of cationic groups with nucleophilic groups | THE DOW CHEMICAL COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927076-B2 | HSP90B N-terminal isoform-selective inhibitors | HSP90AB1, HSP90AB2P, HSP90B1 | ALDH1A1 1671/4885TSHR 4294/4885TDP1 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.