Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934720 | 0.84 | AOC3 (0.37) | ACHETSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL476656 | 0.78 | ACHE (0.41) | ACHETSHRHAO1CA1CA2 | |
| SCHEMBL24181750 | 0.78 | CA1 (0.36) | ACHETSHRCA1CA2CA7 | |
| SCHEMBL9772142 | 0.78 | ALDH1A1 (0.52) | ACHETSHRCA1CA2CA7 | |
| SCHEMBL7189127 | 0.75 | CETP (0.34) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL5726889 | 0.74 | SLC22A12 (0.50) | — | |
| SCHEMBL10294028 | 0.73 | ALOX5AP (0.39) | ACHEHAO1ALDH1A1ARAOC3 | |
| SCHEMBL7111480 | 0.73 | LMNA (0.41) | TSHRHAO1ALDH1A1TDP1ATM | |
| SCHEMBL6863388 | 0.73 | KMT2A (0.54) | TSHRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL24198840 | 0.73 | TDP1 (0.44) | TSHRCA2ALDH1A1TDP1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938253-B2 | Catalysts for efficient Z-selective metathesis | TRUSTEES OF BOSTON COLLEGE (US) | 2018-04-10 | — | — | US | disclosed |
| US-20120172361-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CALIFORNIA CAPITAL EQUITY, LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20070179150-A1 | NITROSATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-7211590-B2 | Nitrosated proton pump inhibitors, compositions and methods of use | NITROMED, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| EP-0452786-B1 | Process for making multilayer coatings | DU PONT (US) | 2001-01-31 | — | — | EP | disclosed |
| US-5880209-A | POLYESTERURETHANE COPOLYMERS WITH NEUTRALIZED ACID GROUPS | HERBERTS GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5721018-A | Method for producing multilayer coatings | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-02-24 | — | — | US | disclosed |
| US-5569705-A | POLYURETHANE RESINS HAVING INTRODUCED DOUBLE BONDS; AUTOMOBILE LACQUERS | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5552227-A | AUTOMOBILES | HERBERTS GMBH (DE) | 1996-09-03 | — | — | US | disclosed |
| EP-0538719-B1 | Process for making multilayers coating | HERBERTS & CO GMBH (DE) | 1996-04-10 | — | — | EP | disclosed |
| EP-0261385-B1 | VEHICLE COMBINATION CURABLE BY CURING AGENTS, FOR USE IN AQUEOUS DILUTABLE COATINGS, CATHODICALLY DEPOSITABLE ELECTROPHORETIC COATING COMPOSITIONS, AND THEIR USE | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0452786-A2 | Process for making multilayer coatings | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1991-10-23 | — | — | EP | disclosed |
| EP-0438090-A1 | Binder composition for the preparation of pigment pastes and aqueous coating compositions containing these pigment pastes | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1991-07-24 | — | — | EP | disclosed |
| US-4909915-A | Water dilutable poly (meth)acrylate containing ionic groups | HERBERTS GESELLSCHAFT MIT BESCHRANKTER (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4880867-A | Aqueous coating compositions, a process for their preparation and method of using the same | 501 HERBERTS GESELLSCHAFT MIT BESCHRANKTER (DE) | 1989-11-14 | — | — | US | disclosed |
| US-4865705-A | Non-auto crosslinking binder combination, aqueous coating compound containing the same and its use | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-12 | — | — | US | disclosed |
| US-4865704-A | HYDROXYL GROUP, AMINO GROUP CONTINING EPOXIDE RESIN, AND AMINO GROUP POLYMER BLEND | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-12 | — | — | US | disclosed |
| EP-0261385-A2 | Vehicle combination curable by curing agents, for use in aqueous dilutable coatings, cathodically depositable electrophoretic coating compositions, and their use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1988-03-30 | — | — | EP | disclosed |
| EP-0260447-A2 | Aqueous coating composition, process for its preparation and its use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0256540-A2 | Aqueous coating, process for its preparation and its use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1988-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172361-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CYP3A5, CYP11B2, ABCB1 | ACHE 2157/4885TSHR 129/4885HAO1 4680/4885 |
| US-20070179150-A1 | NITROSATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE | NOS1, PTGS1, NOS2 | ACHE 964/4885TSHR 3008/4885HAO1 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.