Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751674 | 0.80 | CA2 (0.54) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL88641 | 0.78 | CA2 (0.64) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL57239 | 0.76 | CA2 (0.61) | CA2CA1PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11574583 | 0.76 | CA2 (0.61) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL4438 | 0.74 | CA2 (0.58) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL6239355 | 0.74 | CA2 (0.58) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL22429350 | 0.74 | CA1 (0.46) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL8577557 | 0.74 | CA2 (0.58) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL67309 | 0.74 | CA2 (0.58) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL6239359 | 0.74 | CA2 (0.58) | CA2CA1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708561-B1 | POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREOF | HANMI FINE CHEMICAL CO LTD (KR) | 2024-05-08 | — | — | EP | disclosed |
| EP-3924396-B1 | REVERSE IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-04-19 | — | — | EP | disclosed |
| EP-3924392-B1 | IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-03-22 | — | — | EP | disclosed |
| EP-3924396-A1 | REVERSE IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM | Dow Global Technologies LLC (US) | 2021-12-22 | — | — | EP | disclosed |
| US-11168180-B2 | Polyethylene glycol derivative and preparation method thereof | HANMI FINE CHEMICAL CO., LTD. | 2021-11-09 | — | — | US | disclosed |
| EP-3708561-A2 | POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREOF | Hanmi Fine Chemical Co., Ltd. (KR) | 2020-09-16 | — | — | EP | disclosed |
| WO-2020167600-A1 | REVERSE IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-08-20 | — | — | WO | disclosed |
| US-20200231749-A1 | Polyethylene Glycol Derivative And Preparation Method Thereof | HANMI FINE CHEMICAL CO., LTD. (KR) | 2020-07-23 | — | — | US | disclosed |
| WO-2014089177-A2 | COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-06-12 | — | — | WO | disclosed |
| WO-2011045702-A1 | PYRROLO[2,3-D] PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| US-6656973-B2 | Anticancer chemotherapy, and cytoprotective agents administered before, during or after chemotherapy to protect the normal cells of the patient | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2003-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231749-A1 | Polyethylene Glycol Derivative And Preparation Method Thereof | SI, RPS27A, PGF | CA2 4728/4885CA1 4263/4885PRSS1 4207/4885 |
| US-11168180-B2 | Polyethylene glycol derivative and preparation method thereof | SI, RPS27A, PGF | CA2 4728/4885CA1 4263/4885PRSS1 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.