Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482402 | 0.80 | LMNA (0.42) | LMNAALDH1A1FAAHMAPTUSP2 | |
| SCHEMBL1290659 | 0.78 | ALDH1A1 (0.44) | LMNAALDH1A1FAAHMAPTUSP2 | |
| SCHEMBL63651 | 0.72 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL27082238 | 0.72 | FAAH (0.39) | LMNAALDH1A1FAAHMAPTUSP2 | |
| SCHEMBL27743554 | 0.71 | TSHR (0.34) | ALDH1A1HPGD | |
| SCHEMBL27609652 | 0.71 | TSHR (0.39) | ALDH1A1CYP3A4SMN1; SMN2HPGD | |
| SCHEMBL29056141 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL29187275 | 0.70 | ALDH1A1 (0.38) | LMNAALDH1A1FAAHMAPTMGLL | |
| SCHEMBL1583290 | 0.70 | ALDH1A1 (0.38) | LMNAALDH1A1FAAHMAPTMGLL | |
| SCHEMBL2579460 | 0.70 | ALDH1A1 (0.38) | ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576980-B1 | Surface treatment anneal of hydrogenated silicon-oxy-carbide dielectric layer | AGERE SYSTEMS, INC. | 2003-06-10 | — | — | US | claimed |