Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | METAP2 | P50579 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophanate Methyl SCHEMBL80466 | 0.91 | METAP1 (0.59) | METAP1KDM4ESMN1; SMN2METAP2NPC1 | |
| Carbendazim SCHEMBL18131962 | 0.76 | METAP1 (0.65) | METAP1KDM4ESMN1; SMN2METAP2NPC1 | |
| Thiophanate SCHEMBL8322113 | 0.75 | KMT2A (0.49) | KDM4ENPC1RAB9ATDP1POLB | |
| Thiabendazole SCHEMBL28170923 | 0.75 | METAP1 (0.71) | METAP1KDM4ESMN1; SMN2METAP2NPC1 | |
| Thiabendazole SCHEMBL675655 | 0.74 | METAP1 (0.83) | METAP1KDM4ESMN1; SMN2METAP2NPC1 | |
| Thiabendazole SCHEMBL30099775 | 0.74 | METAP1 (0.83) | METAP1KDM4ESMN1; SMN2METAP2NPC1 | |
| Thiophanate SCHEMBL20842 | 0.74 | ALDH1A1 (0.70) | KDM4ESMN1; SMN2CYP1A2CYP2C19POLB | |
| Thiabendazole SCHEMBL29370729 | 0.74 | METAP1 (1.00) | METAP1KDM4ESMN1; SMN2METAP2NPC1 | |
| Thiophanate SCHEMBL29398343 | 0.74 | ALDH1A1 (0.70) | KDM4ESMN1; SMN2CYP1A2CYP2C19POLB | |
| Thiabendazole SCHEMBL19842 | 0.74 | METAP1 (1.00) | METAP1KDM4ESMN1; SMN2METAP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003077651-A1 | MICROPARTICLE FORMULATION WITH REDUCED AQUATIC TOXICITY | CHEMINOVA A/S (DK) | 2003-09-25 | — | — | WO | disclosed |