Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 9/20 | 0.47 |
| ▸ | THRB | P10828 | 9/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189170 | 0.99 | LTB4R (0.48) | LTB4RTHRATHRBPTPN11MEN1 | |
| SCHEMBL7189191 | 0.97 | PPARG (0.47) | LTB4RTHRATHRBLMNAMAPT | |
| SCHEMBL7194866 | 0.92 | MTNR1A (0.47) | LTB4RLMNAMAPTKMT2APTGES | |
| SCHEMBL7190716 | 0.90 | LMNA (0.54) | LTB4RTHRATHRBPTPN11MEN1 | |
| SCHEMBL7194147 | 0.89 | LMNA (0.52) | LTB4RTHRATHRBPTPN11MEN1 | |
| SCHEMBL7194170 | 0.88 | LTB4R (0.49) | LTB4RTHRATHRBPTPN11MEN1 | |
| SCHEMBL7191712 | 0.88 | THRB (0.50) | LTB4RTHRATHRBPTPN11PTGES | |
| SCHEMBL7188124 | 0.87 | LTB4R (0.47) | LTB4RTHRATHRBPTPN11MEN1 | |
| SCHEMBL7198468 | 0.87 | THRB (0.48) | LTB4RTHRATHRBPTPN11PTGES | |
| SCHEMBL7194122 | 0.86 | THRA (0.49) | LTB4RTHRATHRBMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | LTB4R 506/4885THRA 2660/4885THRB 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.