Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199108 | 0.94 | FFAR1 (0.40) | CHRNA7ACHETDP1ESR1ESR2 | |
| SCHEMBL29184903 | 0.87 | ESR1 (0.46) | ESR1ESR2TSHR | |
| SCHEMBL7203087 | 0.81 | TYR (0.40) | ESR1ESR2ALDH1A1SMN1; SMN2ALOX5 | |
| SCHEMBL9547873 | 0.80 | CHRNA7 (0.42) | CHRNA7ACHETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6962580 | 0.78 | ESR1 (0.62) | TDP1ESR1ESR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12469442 | 0.76 | AOC3 (0.38) | TDP1ESR1ESR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17382854 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL132554 | 0.76 | AOC3 (0.38) | TDP1ESR1ESR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1200882 | 0.76 | TSHR (0.60) | CHRNA7ACHETDP1ESR1ESR2 | |
| SCHEMBL6957145 | 0.76 | MAPT (0.38) | ACHETDP1ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806471-A | Preparation method for preparing substituted propargyl alcohol by catalyzing paraformaldehyde and alkyne with alkali | 延安大学 | 2023-03-17 | — | — | CN | disclosed |
| US-20220144883-A1 | METHODS OF MODIFYING PHOSPHORYLATED OR SULFATED TYROSINE RESIDUES OF POLYPEPTIDES | PHOSFISH LLC | 2022-05-12 | — | — | US | disclosed |
| US-20220127215-A1 | A COPPER-CATALYZED METHOD AND APPLICATION FOR PREPARING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN AS AN OXIDANT | FUDAN UNIVERSITY (CN) | 2022-04-28 | — | — | US | disclosed |
| CN-112979610-B | Diacetylene diol compound, and synthetic method and application thereof | 河南农业大学 | 2022-03-25 | — | — | CN | disclosed |
| EP-3919469-A1 | COPPER-CATALYZED METHOD FOR PREPARING ALDEHYDE OR KETONE COMPOUND BY OXIDIZING ALCOHOL BY USING OXYGEN AS OXIDANT, AND APPLICATION THEREOF | Fudan University (CN) | 2021-12-08 | — | — | EP | disclosed |
| CN-113698411-A | Benzo [ b ] furo [2,3-d ] azepine derivative and synthesis method and application thereof | 临沂大学 | 2021-11-26 | — | — | CN | disclosed |
| WO-2020156238-A1 | COPPER-CATALYZED METHOD FOR PREPARING ALDEHYDE OR KETONE COMPOUND BY OXIDIZING ALCOHOL BY USING OXYGEN AS OXIDANT, AND APPLICATION THEREOF | 复旦大学 | 2020-08-06 | — | — | WO | disclosed |
| US-10383831-B2 | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use | Temple University—Of the Commonwealth System of Higher Education (US) | 2019-08-20 | — | — | US | disclosed |
| US-20180243239-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2018-08-30 | — | — | US | disclosed |
| WO-2017023912-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-02-09 | — | — | WO | disclosed |
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6310049-B1 | 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1104418-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009500-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-24 | — | — | WO | disclosed |
| EP-0360091-B1 | PROCESS FOR THE PREPARATION OF ALKYL-SUBSTITUTED CINNAMIC ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-09-02 | — | — | EP | disclosed |
| US-4996365-A | Preparation of alkyl-substituted cinnamaldehydes | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0360091-A2 | Process for the preparation of alkyl-substituted cinnamic aldehydes | BASF Aktiengesellschaft (DE) | 1990-03-28 | — | — | EP | disclosed |
| US-4568749-A | Certain 5-aryl-2-[(4-aryl)-4-hydroxybutyn-2-yl]-1,2,3,4-γ-carbolines | PFIZER INC. (US) | 1986-02-04 | — | — | US | disclosed |
| US-4510308-A | Process for preparing carboline derivatives | PFIZER INC. (US) | 1985-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144883-A1 | METHODS OF MODIFYING PHOSPHORYLATED OR SULFATED TYROSINE RESIDUES OF POLYPEPTIDES | PTMS, ACP1, SRMS | CHRNA7 4550/4885ACHE 4641/4885TDP1 1062/4885 |
| US-10383831-B2 | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use | CCNY, STS, ARSA | CHRNA7 3674/4885ACHE 3923/4885TDP1 2636/4885 |
| US-20220127215-A1 | A COPPER-CATALYZED METHOD AND APPLICATION FOR PREPARING ALDEHYDES OR KETONES BY OXIDIZING ALCOHOLS WITH OXYGEN AS AN OXIDANT | SOD1, ALDH2, AOC2 | CHRNA7 1805/4885ACHE 1139/4885TDP1 4348/4885 |
| US-20180243239-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | CCNY, STS, ARSA | CHRNA7 3674/4885ACHE 3923/4885TDP1 2636/4885 |
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | CHRNA7 1206/4885ACHE 1338/4885TDP1 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.