Inx-09114

Inx-09114

SCHEMBL720114

C[C@@]1(O)[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 2/20 0.60
P2RY4 P51582 2/20 0.60
TGM2 P21980 1/20 0.58
POLB P06746 1/20 0.57
FUT5 Q11128 1/20 0.56
KRAS P01116 2/20 0.55
P2RY6 Q15077 2/20 0.54
NT5E P21589 1/20 0.53
POLG P54098 1/20 0.52
PNP P00491 1/20 0.51
DCPS Q96C86 1/20 0.49
P2RX3 P56373 3/20 0.49
ENPP1 P22413 2/20 0.49
P2RY1 P47900 2/20 0.49
P2RX1 P51575 2/20 0.49
P2RX4 Q99571 2/20 0.49
P2RY11 Q96G91 1/20 0.49
P2RY12 Q9H244 1/20 0.48
TAS1R3 Q7RTX0 1/20 0.48
TAS1R1 Q7RTX1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Inx-09114 SCHEMBL10819844 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
Inx-09114 SCHEMBL21006183 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
Inx-09114 SCHEMBL13522450 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
Inx-09114 SCHEMBL14946248 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
Inx-09114 SCHEMBL14853807 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
Inx-09114 SCHEMBL14929056 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
Inx-09114 SCHEMBL23319265 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
Inx-09114 SCHEMBL21007234 1.00 P2RY2 (0.60) P2RY2P2RY4TGM2POLBFUT5
SCHEMBL13522449 0.99 TGM2 (0.59) P2RY2P2RY4TGM2POLBFUT5
SCHEMBL1576874 0.99 TGM2 (0.59) P2RY2P2RY4TGM2POLBFUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4531842-A2 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION ATEA Pharmaceuticals, Inc. (US) 2025-04-09 EP disclosed
US-20250082656-A1 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION Atea Pharmaceuticals, Inc. (US) 2025-03-13 US disclosed
CN-119255797-A Dosing regimen for treating dengue infection 阿堤亚制药公司 2025-01-03 CN disclosed
WO-2023230348-A2 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION Atea Pharmaceuticals, Inc. (US) 2023-11-30 WO disclosed
US-20230364121-A1 NIRAN INTERFERING DRUGS FOR SARS-COV-2 MUTANT THERAPY Atea Pharmaceuticals, Inc. (US) 2023-11-16 US disclosed
US-20230364121-A1 NIRAN INTERFERING DRUGS FOR SARS-COV-2 MUTANT THERAPY Atea Pharmaceuticals, Inc. (US) 2023-11-16 US disclosed
EP-4172364-A1 CATALYTICALLY CONTROLLED SEQUENCING BY SYNTHESIS TO PRODUCE SCARLESS DNA Illumina, Inc. (US) 2023-05-03 EP disclosed
CN-115997033-A Catalytic control sequencing by synthetic generation of traceless DNA 伊鲁米纳公司 2023-04-21 CN disclosed
WO-2022108701-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING FLUOROPHORES AND QUENCHERS OR DONORS ILLUMINA, INC. (US) 2022-05-27 WO disclosed
US-20220162680-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING FLUOROPHORES AND QUENCHERS OR DONORS ILLUMINA, INC. (US) 2022-05-26 US disclosed
US-20100003217-A1 Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections CRETTON-SCOTT ERIKA 2010-01-07 US disclosed
US-20090118223-A1 Novel 2'-c-methyl and 4'c-methyl nucleoside derivatives MERCK SHARP & DOHME CORP. 2009-05-07 US disclosed
EP-1915053-A2 NOVEL 2'-C-METHYL AND 4'-C-METHYL NUCLEOSIDE DERIVATIVES Merck & Co., Inc. (US) 2008-04-30 EP disclosed
EP-1905778-A2 Novel 2'-C-methyl nucleoside derivatives Metabasis Therapeutics, Inc. (US) 2008-04-02 EP disclosed
US-20070179114-A1 Novel 2'-C methyl nucleoside derivatives METABASIS THERAPEUTICS, INC. (US) 2007-08-02 US disclosed
US-20070042989-A1 Novel 2'-C-methyl nucleoside derivatives METABASIS THERAPEUTICS, INC. (US) 2007-02-22 US disclosed
WO-2007022073-A2 NOVEL 2'-C-METHYL AND 4'-C-METHYL NUCLEOSIDE DERIVATIVES MERCK & CO., INC. (US) 2007-02-22 WO disclosed
EP-1720556-A2 NOVEL 2'-C-METHYL NUCLEOSIDE DERIVATIVES Merck & Co., Inc. (US) 2006-11-15 EP disclosed
WO-2005084192-A2 NOVEL 2’-C-METHYL NUCLEOSIDE DERIVATIVES MERCK & CO., INC. (US) 2005-09-15 WO disclosed
US-20050182252-A1 Hepatitis C viral infection; 2'-C-beta-methyl-7-deazaadenosine; trans-4-(aryl)-2-(4-nitrophenoxy)-2-oxo-1,3,2-dioxaphosphorinanes METABASIS THERAPEUTICS, INC. 2005-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100003217-A1 Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections HAVCR2, PYGL, GOT1 P2RY2 2250/4885P2RY4 1225/4885TGM2 397/4885
US-20230364121-A1 NIRAN INTERFERING DRUGS FOR SARS-COV-2 MUTANT THERAPY NSUN2, ACE2, PNP P2RY2 1640/4885P2RY4 1725/4885TGM2 394/4885
US-20050182252-A1 Hepatitis C viral infection; 2'-C-beta-methyl-7-deazaadenosine; trans-4-(aryl)-2-(4-nitrophenoxy)-2-oxo-1,3,2-dioxaphosphorinanes MTAP, NT5C3B, ADAR P2RY2 637/4885P2RY4 472/4885TGM2 2235/4885
US-20070042989-A1 Novel 2'-C-methyl nucleoside derivatives NSUN2, NT5C3B, MTAP P2RY2 1553/4885P2RY4 1930/4885TGM2 1465/4885
US-20250082656-A1 DOSAGE REGIMENS FOR TREATMENT OF DENGUE INFECTION FCGR3B, HAVCR2, FCGR2A P2RY2 1380/4885P2RY4 510/4885TGM2 4064/4885
US-20090118223-A1 Novel 2'-c-methyl and 4'c-methyl nucleoside derivatives MTAP, NT5C3B, NSUN2 P2RY2 679/4885P2RY4 413/4885TGM2 1500/4885
US-20070179114-A1 Novel 2'-C methyl nucleoside derivatives NSUN2, NT5C3B, MTAP P2RY2 1647/4885P2RY4 2297/4885TGM2 1522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.