Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.44 |
| ▸ | ADAM10 | O14672 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 6/20 | 0.36 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.36 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.36 |
| ▸ | RPS17 | P08708 | 1/20 | 0.36 |
| ▸ | RPSA | P08865 | 1/20 | 0.36 |
| ▸ | RPS2 | P15880 | 1/20 | 0.36 |
| ▸ | RPL35A | P18077 | 1/20 | 0.36 |
| ▸ | RPL7 | P18124 | 1/20 | 0.36 |
| ▸ | RPL17 | P18621 | 1/20 | 0.36 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.36 |
| ▸ | RPS3 | P23396 | 1/20 | 0.36 |
| ▸ | RPS12 | P25398 | 1/20 | 0.36 |
| ▸ | RPL13 | P26373 | 1/20 | 0.36 |
| ▸ | RPL10 | P27635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205516 | 0.88 | ADAM10 (0.51) | MMP2ADAM10MMP13DRD4HDAC4 | |
| SCHEMBL7204290 | 0.88 | MMP2 (0.46) | MMP2ADAM10MMP13HDAC4MMP1 | |
| SCHEMBL7201786 | 0.85 | MMP2 (0.49) | MMP2ADAM10MMP9MMP13DRD4 | |
| SCHEMBL7201610 | 0.85 | MMP2 (0.47) | MMP2ADAM10MMP9MMP3MMP13 | |
| SCHEMBL7204534 | 0.83 | USP5 (0.41) | MMP2ADAM10MMP9MMP3MMP13 | |
| SCHEMBL7203079 | 0.83 | HTR2C (0.47) | MMP2ADAM10MMP13KCNH2ALDH1A1 | |
| SCHEMBL7203215 | 0.83 | MMP2 (0.51) | MMP2ADAM10MMP9MMP3MMP13 | |
| SCHEMBL7200489 | 0.82 | USP5 (0.44) | MMP2ADAM10MMP9MMP13KCNH2 | |
| SCHEMBL7205353 | 0.81 | CARM1 (0.42) | MMP2ADAM10MMP13HDAC4MMP1 | |
| SCHEMBL7205659 | 0.79 | TP53 (0.41) | MMP2ADAM10MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608104-B2 | Antiarthritic agents; anticancer agents | PFIZER INC | 2003-08-19 | — | — | US | disclosed |
| US-20020019534-A1 | Gem substituted hydroxamic acids | PFIZER INC. | 2002-02-14 | — | — | US | disclosed |
| EP-1138680-A1 | Gem substituted sulfonyl hydroxamic acids as MMP inhibitors | Pfizer Products Inc. (US) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019534-A1 | Gem substituted hydroxamic acids | MMP14, TOP2A, ADAMTS1 | MMP2 13/4885ADAM10 254/4885MMP9 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.