Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4329729 | 0.90 | — | — | |
| Bromide SCHEMBL8160255 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL7978126 | 0.72 | — | — | |
| Chloromethane SCHEMBL8460733 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL4066832 | 0.68 | ANPEP (0.31) | — | |
| Hydrochloric Acid SCHEMBL4057967 | 0.67 | — | — | |
| SCHEMBL8037243 | 0.62 | ALDH1A1 (0.33) | — | |
| SCHEMBL27510575 | 0.57 | RECQL (0.30) | — | |
| Potassium Ion SCHEMBL18247779 | 0.56 | LMNA (0.41) | — | |
| SCHEMBL3823029 | 0.55 | GABRA1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751182-B1 | Olefin thermoplastic elastomer compositions | MITSUI CHEMICALS INC (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-6015625-A | COMPOSITION CONTAINING ALPHA-OLEFIN/AROMATIC VINYL COMPOUND RANDOM COPOLYMER GRAFT MODIFIED WITH UNSATURATED CARBOXYLIC ACID OR DERIVATIVE | MITSUI CHEMICALS, INC. (JP) | 2000-01-18 | — | — | US | disclosed |