SCHEMBL7202257

SCHEMBL7202257

Oc1ccc(OOc2ccccc2)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.45
CYP1A2 P05177 1/20 0.45
TTR P02766 2/20 0.44
LTA4H P09960 1/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
TYR P14679 1/20 0.42
CAMK2A Q9UQM7 1/20 0.40
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9645412 0.82 TTR (0.65) ALOX5TTRLTA4HNR1H2BAX
SCHEMBL7191128 0.79 CA2 (0.50) LTA4HNR1H2BAXMEN1USP2
SCHEMBL7191617 0.78 TTR (0.73) TTRGAA
SCHEMBL7196265 0.77 KMT2A (0.43) CYP1A2TTRLTA4HNR1H2BAX
SCHEMBL27735401 0.75 LTA4H (0.71) CYP1A2LTA4HNR1H2BAXTYR
SCHEMBL7183343 0.75 LTA4H (0.46) CYP1A2LTA4HNR1H2BAXMEN1
SCHEMBL7535559 0.74 KMT2A (0.44) CYP1A2MEN1GAAKMT2A
SCHEMBL2859448 0.74 CYP3A4 (0.50) CYP1A2LTA4HNR1H2BAX
SCHEMBL2198518 0.73 MAOB (0.44) ALOX5TTRTYRMEN1KMT2A
SCHEMBL10902147 0.73 TTR (0.54) ALOX5TTRLTA4HNR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 ALOX5 884/4885CYP1A2 1275/4885TTR 2691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.