Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17093429 | 0.79 | CTSL (0.42) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL10498731 | 0.63 | ALDH1A1 (0.50) | ALDH1A1HPGDGFERRECQLKMT2A | |
| Bromide SCHEMBL7203345 | 0.63 | ALDH1A1 (0.47) | HDAC3CA12CA1IDO1ALOX15 | |
| Benzamidoxime SCHEMBL194059 | 0.62 | HDAC8 (0.50) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL2481899 | 0.62 | NPSR1 (0.46) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL4649406 | 0.62 | MEN1 (0.50) | ALOX15ALDH1A1HPGDGFERBLM | |
| SCHEMBL2892980 | 0.61 | TDP1 (0.46) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL12629713 | 0.61 | ALDH1A1 (0.53) | HDAC3CA12CA1IDO1ALOX15 | |
| Benzamidoxime SCHEMBL28112602 | 0.61 | ALOX15 (0.48) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL752522 | 0.60 | ALDH1A1 (0.41) | CA12CA1CA9HSD17B10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599943-B1 | Preventive treatment, related to the radical generating nature of the xanthine dehydrogenase/xanthine oxidase | WAPHARM AB (SE) | 2003-07-29 | — | — | US | disclosed |
| EP-1007025-A1 | USE OF HYDROXYGUANIDINES | Wa Pharm AB (SE) | 2000-06-14 | — | — | EP | disclosed |
| WO-1998023267-A1 | USE OF HYDROXYGUANIDINES | WAPHARM AB (SE) | 1998-06-04 | — | — | WO | disclosed |