Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7209697

[Cl-].[Cl-].[Zr+2]C1=C(C2c3ccccc3-c3ccccc32)C=CC1=[Si](Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.38
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7205244 0.78 HTR2A (0.37) HTR2A
Hydrochloric Acid SCHEMBL7203180 0.78 HTR2A (0.39) HTR2A
Hydrochloric Acid SCHEMBL7205527 0.72 HTR2A (0.34) HTR2AMAPT
Hydrochloric Acid SCHEMBL8390027 0.72 HTR2A (0.34) HTR2AMAPT
Hydrochloric Acid SCHEMBL7203692 0.69 HTR2A (0.38) HTR2AMAPT
Hydrochloric Acid SCHEMBL2353823 0.67 HTR2A (0.33) HTR2A
Hydrochloric Acid SCHEMBL3783189 0.66 HTR2A (0.35) HTR2A
Hydrochloric Acid SCHEMBL8927357 0.65 HTR2A (0.32) HTR2A
Bromide SCHEMBL7205884 0.63 HTR2A (0.35) HTR2A
SCHEMBL6659162 0.61 HTR2A (0.36) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891382-B1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LTD (JP) 2003-05-28 EP disclosed