Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719730 | 1.00 | TSHR (0.54) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL718486 | 1.00 | TSHR (0.54) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL718848 | 0.98 | TSHR (0.51) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL720282 | 0.95 | TSHR (0.47) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL1264169 | 0.89 | THRB (0.47) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL3681594 | 0.85 | TSHR (0.51) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL3447994 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL346466 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL346923 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL345787 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2902007-B1 | DENTAL FILLING REPAIRING MATERIAL | TOKUYAMA DENTAL CORP (JP) | 2019-01-09 | — | — | EP | disclosed |
| US-9533070-B2 | Therapeutic agent for pulmonary emphysema | TERUMO KABUSHIKI KAISHA (JP) | 2017-01-03 | — | — | US | disclosed |
| US-9192693-B2 | Method for treatment of emphysema | TERUMO KABUSHIKI KAISHA (JP) | 2015-11-24 | — | — | US | disclosed |
| US-20150272833-A1 | Dental Restorative Material | TOKUYAMA DENTAL CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| EP-2902007-A1 | DENTAL FILLING REPAIRING MATERIAL | Tokuyama Dental Corporation (JP) | 2015-08-05 | — | — | EP | disclosed |
| US-8835675-B2 | Polymerizable phosphonic acid derivative and adhesive composition comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2014-09-16 | — | — | US | disclosed |
| US-20130178426-A1 | THERAPEUTIC AGENT FOR PULMONARY EMPHYSEMA | TERUMO KABUSHIKI KAISHA (JP) | 2013-07-11 | — | — | US | disclosed |
| EP-2609940-A1 | THERAPEUTIC AGENT FOR PULMONARY EMPHYSEMA | Terumo Kabushiki Kaisha (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-20120053566-A1 | METHOD FOR TREATMENT OF EMPHYSEMA | TERUMO KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120053513-A1 | METHOD FOR TREATMENT OF EMPHYSEMA | TERUMO KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20090048426-A1 | POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048426-A1 | POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME | PTK2, ITGA1, ACTN1 | TSHR 3260/4885TDP1 1316/4885POLB 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.