Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720387 | 1.00 | TSHR (0.54) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL718486 | 1.00 | TSHR (0.54) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL718848 | 0.98 | TSHR (0.51) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL720282 | 0.95 | TSHR (0.47) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL1264169 | 0.89 | THRB (0.47) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL3681594 | 0.85 | TSHR (0.51) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL3447994 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL346466 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL346923 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL345787 | 0.82 | TSHR (0.62) | TSHRTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240164993-A1 | ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME | KURARAY NORITAKE DENTAL INC. (JP) | 2024-05-23 | — | — | US | disclosed |
| EP-4364718-A1 | DENTAL CURABLE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2024-05-08 | — | — | EP | disclosed |
| US-20240139078-A1 | DENTAL FILLING KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2024-05-02 | — | — | US | disclosed |
| EP-4360609-A1 | DENTAL ADHESIVE KIT | Kuraray Noritake Dental Inc. (JP) | 2024-05-01 | — | — | EP | disclosed |
| WO-2024053223-A1 | CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT | クラレノリタケデンタル株式会社 | 2024-03-14 | — | — | WO | disclosed |
| EP-4324450-A1 | DENTAL FILLING KIT | Kuraray Noritake Dental Inc. (JP) | 2024-02-21 | — | — | EP | disclosed |
| EP-4268791-A1 | ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME | Kuraray Noritake Dental Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| EP-3730121-B1 | DENTAL ADHESIVE MATERIAL KIT | KURARAY NORITAKE DENTAL INC (JP) | 2023-10-25 | — | — | EP | disclosed |
| WO-2023127794-A1 | DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER | クラレノリタケデンタル株式会社 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023106419-A1 | DENTAL CURABLE COMPOSITION | クラレノリタケデンタル株式会社 | 2023-06-15 | — | — | WO | disclosed |
| US-8158694-B2 | Single component dental composition containing silane coupling agent and acidic group containing polymerizable monomer | KABUSHIKI KAISHA SHOFU (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20120053566-A1 | METHOD FOR TREATMENT OF EMPHYSEMA | TERUMO KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120053513-A1 | METHOD FOR TREATMENT OF EMPHYSEMA | TERUMO KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20110112209-A1 | SINGLE-COMPONENT DENTAL COMPOSITION CONTAINING SILANE COUPLING AGENT AND ACIDIC GROUP-CONTAINING POLYMERIZABLE MONOMER | TANAKA HISAKI | 2011-05-12 | — | — | US | disclosed |
| US-7879924-B2 | Dental composite resin cement, dental primer and dental adhesive kit containing them | KABUSHIKI KAISHA SHOFU (JP) | 2011-02-01 | — | — | US | disclosed |
| US-7776936-B2 | One-pack type dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | KABUSHIKI KAISHA SHOFU | 2010-03-18 | — | — | US | disclosed |
| US-20090076182-A1 | One-pack type dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-2036532-A2 | One pack type dental adhesive composition | Kabushiki Kaisha Shofu (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | CAD, ITGA1, CIB1 | TSHR 4642/4885TDP1 4439/4885POLB 3832/4885 |
| US-20240139078-A1 | DENTAL FILLING KIT | DHX29, DHX35, DHX15 | TSHR 4803/4885TDP1 2207/4885POLB 499/4885 |
| US-20110112209-A1 | SINGLE-COMPONENT DENTAL COMPOSITION CONTAINING SILANE COUPLING AGENT AND ACIDIC GROUP-CONTAINING POLYMERIZABLE MONOMER | CAD, ITGA1, CIB1 | TSHR 4642/4885TDP1 4439/4885POLB 3832/4885 |
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | CDH1, JMJD7, WDR91 | TSHR 4536/4885TDP1 2986/4885POLB 2272/4885 |
| US-20090076182-A1 | One-pack type dental adhesive composition | DSC1, ITGA1, CAD | TSHR 4689/4885TDP1 3567/4885POLB 3491/4885 |
| US-20240164993-A1 | ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME | MSL1, ITGA1, ASH2L | TSHR 4172/4885TDP1 2204/4885POLB 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.