Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203928 | 0.89 | ALDH1A1 (0.52) | KMT2AMEN1MAPTGAAPTGS1 | |
| SCHEMBL6170675 | 0.84 | MAP2 (0.44) | KMT2AMEN1MAPTPTGS1PTGS2 | |
| SCHEMBL6168282 | 0.80 | PTGS2 (0.68) | KMT2AMEN1MAPTGAAPTGS1 | |
| SCHEMBL27569322 | 0.80 | KMT2A (0.46) | KMT2AMEN1MAPTGAAPTGS1 | |
| SCHEMBL8140742 | 0.79 | MEN1 (0.48) | KMT2AMEN1MAPTGAAPTGS1 | |
| SCHEMBL8140740 | 0.78 | MEN1 (0.49) | KMT2AMEN1MAPTGAAPTGS1 | |
| SCHEMBL6170113 | 0.78 | ENPP2 (0.43) | KMT2AMEN1MAPTPTGS1PTGS2 | |
| SCHEMBL6170210 | 0.75 | MAP2 (0.46) | KMT2AMEN1MAPTPTGS1PTGS2 | |
| SCHEMBL7206101 | 0.74 | ALDH1A1 (0.48) | KMT2AMEN1MAPTGAAPTGS2 | |
| SCHEMBL6172849 | 0.74 | ALDH1A1 (0.42) | KMT2AMEN1MAPTGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045833-B1 | 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS | PFIZER (US) | 2005-11-02 | — | — | EP | disclosed |