Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207482 | 0.89 | LMNA (0.35) | LMNAALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL3825844 | 0.86 | LMNA (0.41) | LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL7204740 | 0.84 | TSHR (0.38) | LMNAALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL7212661 | 0.81 | CSNK2A2 (0.37) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL7206799 | 0.79 | LMNA (0.33) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7212657 | 0.76 | NAAA (0.43) | RECQLLMNAMEN1KMT2AGAA | |
| SCHEMBL7205833 | 0.74 | ALDH1A1 (0.42) | RECQLLMNAALDH1A1MAPTHSD17B10 | |
| SCHEMBL7205752 | 0.73 | BCHE (0.41) | ALDH1A1ACHEBCHE | |
| SCHEMBL7212676 | 0.73 | RAF1 (0.33) | KMT2A | |
| SCHEMBL8196590 | 0.72 | LMNA (0.61) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |