Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648365 | 0.71 | GPR55 (0.50) | ALDH1A1NPSR1GPR55P2RX7LMNA | |
| SCHEMBL29171626 | 0.71 | PTPN1 (0.53) | SMN1; SMN2ALDH1A1GPR55P2RX7LMNA | |
| SCHEMBL28093665 | 0.70 | P2RX7 (0.61) | ALDH1A1NPSR1P2RX7EPHX2LMNA | |
| SCHEMBL2361439 | 0.70 | GSK3B (0.42) | — | |
| SCHEMBL7900490 | 0.69 | CNR2 (0.53) | ALDH1A1GPR55P2RX7EPHX2KMT2A | |
| SCHEMBL29112033 | 0.68 | MEN1 (0.41) | ALDH1A1EPHX2LMNAKMT2A | |
| SCHEMBL7900604 | 0.68 | CNR2 (0.57) | ALDH1A1P2RX7EPHX2KMT2A | |
| SCHEMBL15113225 | 0.66 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1NPSR1P2RX7EPHX2 | |
| SCHEMBL1397704 | 0.64 | P2RX7 (0.53) | SMN1; SMN2ALDH1A1NPSR1P2RX7EPHX2 | |
| SCHEMBL17281531 | 0.63 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1NPSR1P2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |