Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208761 | 0.82 | BCHE (0.39) | SMN1; SMN2BCHEMGLLALDH1A1TSHR | |
| SCHEMBL7206793 | 0.80 | BCHE (0.39) | SMN1; SMN2BCHEMGLLALDH1A1TSHR | |
| SCHEMBL7205752 | 0.80 | BCHE (0.41) | SMN1; SMN2BCHEMGLLALDH1A1TSHR | |
| SCHEMBL7212661 | 0.73 | CSNK2A2 (0.37) | TSHRMEN1KMT2A | |
| SCHEMBL8194040 | 0.71 | MEN1 (0.40) | SMN1; SMN2FAAHMGLLALDH1A1ALOX15 | |
| SCHEMBL7211153 | 0.70 | KDM4E (0.30) | ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL7212657 | 0.69 | NAAA (0.43) | SMN1; SMN2BCHEMGLLMEN1KMT2A | |
| SCHEMBL7206447 | 0.68 | LMNA (0.49) | SMN1; SMN2TSHRMAPT | |
| SCHEMBL22807064 | 0.64 | ALDH1A1 (0.41) | SMN1; SMN2FAAHMGLLALDH1A1ALOX15 | |
| SCHEMBL21807844 | 0.61 | SMN1; SMN2 (0.43) | SMN1; SMN2FAAHMGLLALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |