Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211139 | 0.78 | SMN1; SMN2 (0.34) | ALDH1A1MAPTTSHR | |
| SCHEMBL3825844 | 0.77 | LMNA (0.41) | KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL7205752 | 0.76 | BCHE (0.41) | ALDH1A1TSHR | |
| SCHEMBL7212676 | 0.76 | RAF1 (0.33) | — | |
| SCHEMBL7204740 | 0.76 | TSHR (0.38) | KDM4EALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL7207482 | 0.75 | LMNA (0.35) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL7204392 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL7205833 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7205105 | 0.73 | RECQL (0.37) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7205111 | 0.70 | LMNA (0.52) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |