Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481389 | 0.88 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL418525 | 0.87 | ALDH1A1 (0.59) | MTNR1AMTNR1BALDH1A1KDM4EHRH3 | |
| SCHEMBL6512056 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1KDM4EHRH3 | |
| SCHEMBL9808184 | 0.83 | ALDH1A1 (0.56) | MTNR1AMTNR1BALDH1A1KDM4EHRH3 | |
| SCHEMBL27523394 | 0.83 | APP (0.52) | MTNR1AMTNR1BALDH1A1KDM4EHRH3 | |
| SCHEMBL8639268 | 0.83 | ALDH1A1 (0.53) | MTNR1AMTNR1BALDH1A1KDM4ENPC1 | |
| SCHEMBL5167250 | 0.83 | ALDH1A1 (0.56) | MTNR1AMTNR1BALDH1A1KDM4EHRH3 | |
| SCHEMBL8637757 | 0.82 | CA2 (0.61) | ALDH1A1KDM4EAPPNPC1RAB9A | |
| SCHEMBL6123648 | 0.81 | ALDH1A1 (0.54) | MTNR1AMTNR1BALDH1A1KDM4EHRH3 | |
| SCHEMBL9770431 | 0.81 | ALDH1A1 (0.54) | MTNR1AMTNR1BALDH1A1KDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12286426-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | Université de Montréal (CA) | 2025-04-29 | — | — | US | disclosed |
| EP-3704111-B1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | UNIV MONTREAL (CA) | 2024-10-09 | — | — | EP | disclosed |
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |
| US-20230357221-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | UNIV MONTREAL (CA) | 2023-11-09 | — | — | US | disclosed |
| US-11760754-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | Université de Montréal (CA) | 2023-09-19 | — | — | US | disclosed |
| US-20210387980-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | Université de Montréal (CA) | 2021-12-16 | — | — | US | disclosed |
| CN-111886234-A | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2020-11-03 | — | — | CN | disclosed |
| EP-3704111-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | Université de Montréal (CA) | 2020-09-09 | — | — | EP | disclosed |
| US-9353142-B2 | Protecting group for indole group, nucleic acid-synthesizing amidite and nucleic acid-synthesizing method | APTA BIOSCIENCES LTD. (GB) | 2016-05-31 | — | — | US | disclosed |
| US-9353142-B2 | Protecting group for indole group, nucleic acid-synthesizing amidite and nucleic acid-synthesizing method | APTA BIOSCIENCES LTD. (GB) | 2016-05-31 | — | — | US | disclosed |
| US-20140256928-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | APTA BIOSCIENCES LTD. (GB) | 2014-09-11 | — | — | US | disclosed |
| US-20140256928-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | APTA BIOSCIENCES LTD. (GB) | 2014-09-11 | — | — | US | disclosed |
| US-8759502-B2 | Protecting group for indole group, nucleic acid-synthesizing amidite and nucleic acid-synthesizing method | APTA BIOSCIENCES LTD. (GB) | 2014-06-24 | — | — | US | disclosed |
| US-8759502-B2 | Protecting group for indole group, nucleic acid-synthesizing amidite and nucleic acid-synthesizing method | APTA BIOSCIENCES LTD. (GB) | 2014-06-24 | — | — | US | disclosed |
| US-20110118455-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | FUJITSU LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110118455-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | FUJITSU LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-0939628-B1 | THIOL SULFONE METALLOPROTEASE INHIBITORS | MONSANTO CO (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6013649-A | BOND DISORDERS; AUTOIMMUNE DISEASES; ANTITUMOR AGENTS | MONSANTO COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256928-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | INMT, NSUN2, RNMT | MTNR1A 300/4885MTNR1B 1178/4885ALDH1A1 2229/4885 |
| US-20230357221-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | IDH2, TFAM, IDH1 | MTNR1A 3872/4885MTNR1B 4160/4885ALDH1A1 2036/4885 |
| US-20110118455-A1 | PROTECTING GROUP FOR INDOLE GROUP, NUCLEIC ACID-SYNTHESIZING AMIDITE AND NUCLEIC ACID-SYNTHESIZING METHOD | INMT, NSUN2, RNMT | MTNR1A 300/4885MTNR1B 1178/4885ALDH1A1 2229/4885 |
| US-12286426-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | IDH2, TFAM, IDH1 | MTNR1A 3872/4885MTNR1B 4160/4885ALDH1A1 2036/4885 |
| US-20210387980-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | IDH2, TFAM, NUTF2 | MTNR1A 3850/4885MTNR1B 4165/4885ALDH1A1 2100/4885 |
| US-11760754-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | IDH2, TFAM, NUTF2 | MTNR1A 3850/4885MTNR1B 4165/4885ALDH1A1 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.