Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 3/20 | 0.35 |
| ▸ | TDP2 | O95551 | 2/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680308 | 0.73 | MAPT (0.46) | NPC1MAPTL3MBTL1RAB9AMEN1 | |
| SCHEMBL7771196 | 0.69 | MAOA (0.40) | NPC1MAPTL3MBTL1RAB9AMEN1 | |
| SCHEMBL10813403 | 0.65 | TOP2B (0.45) | MAPTL3MBTL1MEN1KMT2ANSD2 | |
| SCHEMBL11124665 | 0.65 | MAPT (0.31) | MAPT | |
| SCHEMBL7208669 | 0.62 | TERT (0.43) | NPC1MAPTL3MBTL1RAB9AMEN1 | |
| SCHEMBL728510 | 0.62 | MEN1 (0.60) | MAPTL3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL10891900 | 0.62 | POLB (0.35) | MAPTL3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL7122665 | 0.61 | MEN1 (0.54) | NPC1MAPTL3MBTL1RAB9AMEN1 | |
| SCHEMBL7129845 | 0.61 | L3MBTL1 (0.53) | NPC1MAPTL3MBTL1RAB9AMEN1 | |
| SCHEMBL7208670 | 0.60 | TERT (0.46) | NPC1MAPTL3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710689-B1 | Polymeric antitumor agents | WYETH CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-5609867-A | POLYAMIDES FROM DIAMINE MONOMERS CONTAINING ANTHRAQUINONE, ANTHRAPYRAZOLE, AZA-ANTHRAQUINONE, AND DIAZA-ANTHRAQUINONE RINGS | AMERICAN CYANAMID COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0710689-A2 | Polymeric antitumor agents | American Cyanamid Company (US) | 1996-05-08 | — | — | EP | disclosed |
| US-4715993-A | FROM SALTS, USING AMMONIA OR METHYLAMINE | AMERICAN CYANAMID COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0122417-A3 | POLYMERIC(((OXAZOLIDINYL)ALKYL)AMINO)ANTHRAQUINONES | AMERICAN CYANAMID COMPANY (US) | 1986-01-08 | — | — | EP | disclosed |
| US-4526788-A | Polymeric[[(oxazolidinyl)alkyl]amino]anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| US-4526788-A | Polymeric[[(oxazolidinyl)alkyl]amino]anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0122417-A2 | Polymeric(((oxazolidinyl)alkyl)amino)anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |
| EP-0122417-A2 | Polymeric(((oxazolidinyl)alkyl)amino)anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |