Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26667254 | 0.85 | CXCR4 (0.61) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL20221777 | 0.83 | HPGD (0.70) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL20346420 | 0.82 | HPGD (0.64) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL20651150 | 0.81 | HPGD (0.58) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6263973 | 0.81 | HPGD (0.68) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8811234 | 0.81 | HPGD (0.68) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL408382 | 0.81 | HPGD (1.00) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL601473 | 0.80 | NPC1 (1.00) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12897993 | 0.79 | HPGD (0.70) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL21336118 | 0.79 | HPGD (0.64) | HPGDNPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3624791-B1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | UNIV CITY NEW YORK RES FOUND (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20240000964-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME | AJINOMOTO CO., INC. (JP) | 2024-01-04 | — | — | US | disclosed |
| WO-2022154127-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED THEREFROM | 味の素株式会社 | 2022-07-21 | — | — | WO | disclosed |
| US-11000604-B2 | Reagent for site-selective bioconjugation of proteins or antibodies | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2021-05-11 | — | — | US | disclosed |
| US-11000604-B2 | Reagent for site-selective bioconjugation of proteins or antibodies | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200397928-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2020-12-24 | — | — | US | disclosed |
| US-20200397928-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2020-12-24 | — | — | US | disclosed |
| EP-3624791-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | Research Foundation Of The City University Of New York (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018213537-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2018-11-22 | — | — | WO | disclosed |
| US-8618145-B2 | Small molecular compounds capable of accelerating proliferation of stem cells and use thereof | HAN MEI (CN) | 2013-12-31 | — | — | US | disclosed |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | HAN MEI (CN) | 2012-03-01 | — | — | US | disclosed |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | HAN MEI (CN) | 2012-03-01 | — | — | US | disclosed |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | HAN MEI (CN) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000964-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME | SSB, CTH, SCLY | HPGD 3745/4885NPC1 3657/4885RAB9A 331/4885 |
| US-20200397928-A1 | REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES | MRPL21, TFRC, ARGLU1 | HPGD 4642/4885NPC1 4336/4885RAB9A 2630/4885 |
| US-11000604-B2 | Reagent for site-selective bioconjugation of proteins or antibodies | MRPL21, TFRC, ARGLU1 | HPGD 4642/4885NPC1 4336/4885RAB9A 2630/4885 |
| US-20120053214-A1 | THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF | MKI67, KIT, PCNA | HPGD 1307/4885NPC1 2926/4885RAB9A 2617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.