Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7213150

CC(C)(C)c1cc([O-])cc(C(C)(C)C)c1.CC(C)(C)c1cccc([O-])c1.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Al+3].[Al+3]

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
GPR3 P46089 2/20 0.38
PTPN1 P18031 1/20 0.38
KCNH2 Q12809 6/20 0.34
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL7089713 0.95 ACHE (0.42) ACHEHDAC4HDAC2HDAC8GPR3
Trifluoromethanesulfonic Acid SCHEMBL7086757 0.89 GPR3 (0.38) ACHEGPR3PTPN1KCNH2ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL7089707 0.77 GABRA1 (0.39) ACHEHDAC4HDAC2HDAC8PTPN1
Lithium Ion SCHEMBL31616213 0.76 HDAC8 (0.45) ACHEHDAC4HDAC2HDAC8NPC1
Potassium Ion SCHEMBL11867561 0.76 HDAC8 (0.45) ACHEHDAC4HDAC2HDAC8NPC1
Hydrochloric Acid SCHEMBL6040014 0.74 KIF11 (0.47) ACHEHDAC4HDAC2HDAC8NPC1
Trifluoromethanesulfonic Acid SCHEMBL7089263 0.74 GPR3 (0.44) ACHEGPR3PTPN1KCNH2
Trifluoromethanesulfonic Acid SCHEMBL7089027 0.72 GPR3 (0.43) ACHEGPR3PTPN1KCNH2
Trifluoromethanesulfonic Acid SCHEMBL7086264 0.72 GPR3 (0.40) ACHEGPR3KCNH2ALDH1A1
1-Hydroxy-3-Methoxybenzene SCHEMBL7085847 0.72 KCNH2 (0.49) ACHEGPR3KCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624321-B2 Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate BAYER AKTIENGESELLSCHAFT (DE) 2003-09-23 US disclosed