Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219252 | 0.84 | ELANE (0.39) | KMT2ALMNAMEN1 | |
| SCHEMBL7220659 | 0.82 | NPSR1 (0.44) | GRM2KMT2ALMNAGAADAO | |
| SCHEMBL29003556 | 0.66 | ADAM17 (0.37) | ITGALADAM17KMT2AALDH1A1SLC6A2 | |
| SCHEMBL25383979 | 0.64 | PPARG (0.38) | GRM2LMNADAOALDH1A1POLB | |
| SCHEMBL14592561 | 0.62 | SSTR1 (0.41) | GRM2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL7213679 | 0.62 | ADAM17 (0.35) | ITGALADAM17KMT2ALMNAALDH1A1 | |
| SCHEMBL9506152 | 0.61 | P2RX7 (0.35) | GRM2LMNAGAAALDH1A1CHRNA1 | |
| SCHEMBL9506159 | 0.61 | CHRNA1 (0.38) | KMT2ALMNACHRNA1CHRNGCHRNB1 | |
| SCHEMBL6112974 | 0.61 | — | — | |
| SCHEMBL19566023 | 0.59 | KMT2A (0.35) | ADAM17KMT2ALMNAALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |