Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.42 |
| ▸ | CTSS | P25774 | 14/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219805 | 0.83 | NOS2 (0.42) | CTSKCTSSMAPK1 | |
| SCHEMBL7213748 | 0.75 | KDM4E (0.44) | CTSKCTSSMAPK1RECQL | |
| SCHEMBL16389942 | 0.74 | NOS3 (0.40) | CTSKCTSS | |
| SCHEMBL7215442 | 0.71 | L3MBTL1 (0.40) | KDM5AMAPK1 | |
| SCHEMBL10504739 | 0.71 | MAPK1 (0.46) | CTSKCTSSMAPK1RECQL | |
| SCHEMBL7213760 | 0.70 | NOS2 (0.40) | KDM5AMAPK1RECQL | |
| SCHEMBL7219012 | 0.70 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL25537805 | 0.68 | CTSK (0.41) | CTSKCTSS | |
| SCHEMBL6657408 | 0.68 | KDM4E (0.38) | MAPK1RECQL | |
| SCHEMBL7219021 | 0.67 | AR (0.37) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |