Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14961084 | 0.89 | TRPM8 (0.63) | LTA4HPLA2G2ATRPM8FAAHMTNR1A | |
| SCHEMBL6927448 | 0.87 | MTNR1A (0.74) | FAAHMTNR1AMTNR1BHTR1AKMT2A | |
| SCHEMBL15996572 | 0.87 | TRPM8 (0.61) | LTA4HPLA2G2ATRPM8FAAHMTNR1A | |
| SCHEMBL8880324 | 0.86 | MTNR1A (0.60) | LTA4HPLA2G2ATRPM8FAAHMTNR1A | |
| SCHEMBL8880875 | 0.85 | MTNR1A (0.59) | LTA4HPLA2G2ATRPM8FAAHMTNR1A | |
| SCHEMBL8629672 | 0.85 | MTNR1A (0.65) | LTA4HPLA2G2ATRPM8FAAHMTNR1A | |
| SCHEMBL14907340 | 0.85 | HTR1A (0.66) | LTA4HPLA2G2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL14907343 | 0.85 | HTR1A (0.66) | LTA4HPLA2G2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL30418479 | 0.84 | TRPV1 (0.66) | FAAHMTNR1AMTNR1BHTR1AKMT2A | |
| SCHEMBL25734745 | 0.84 | TRPV1 (0.66) | FAAHMTNR1AMTNR1BHTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589953-B2 | Treatment of anxiety, depression, aggressiveness, panic attacks, obsessive-compulsive disorders, schizophrenia, suicidal tendency, neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease | PIERRE FABRE MEDICAMENT (FR) | 2003-07-08 | — | — | US | disclosed |
| US-20020061891-A1 | Indole derivatives as 5-HT1B and 5-HT1D agonists | PEREZ MICHEL (FR) | 2002-05-23 | — | — | US | disclosed |
| US-6277853-B1 | FOR TREATMENT OF NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS, MIGRAINES, ALCOHOLISM | PIERRE FABRE MEDICAMENT (FR) | 2001-08-21 | — | — | US | disclosed |
| US-5726177-A | HEADACHES; ANXIOLYTIC AGENTS, ANTIDEPRESSANTS, ANALGESICS | PIERRE FABRE MEDICAMENT (FR) | 1998-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061891-A1 | Indole derivatives as 5-HT1B and 5-HT1D agonists | HTR1B, HTR1A, HTR1D | LTA4H 842/4885PLA2G2A 1255/4885TRPM8 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.