Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972130 | 0.89 | ALOX5 (0.44) | ALDH1A1HPGDSMN1; SMN2MAPTALOX5 | |
| SCHEMBL7974639 | 0.79 | CHRM5 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6NPSR1 | |
| SCHEMBL7971923 | 0.76 | CHRM5 (0.47) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9338868 | 0.72 | NFE2L2 (0.49) | ALDH1A1HPGDSMN1; SMN2MAPTALOX5 | |
| SCHEMBL8436212 | 0.71 | CYP11B2 (0.39) | MAPTMAOBPADI4 | |
| SCHEMBL7969830 | 0.71 | TP53 (0.43) | MAPTALOX5MEN1TP53CYP1A2 | |
| SCHEMBL17608809 | 0.71 | LMNA (0.44) | CYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL30715053 | 0.71 | TERT (0.45) | ALDH1A1HPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL29195023 | 0.71 | TERT (0.45) | ALDH1A1HPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL9161972 | 0.70 | NFE2L2 (0.47) | ALDH1A1HPGDSMN1; SMN2MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573275-B1 | Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. | SYNGENTA LIMITED (GB) | 2003-06-03 | — | — | US | disclosed |